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Mycobacterium tuberculosis complex lineage 5 exhibits high levels of within-lineage genomic diversity and differing gene content compared to the type strain H37Rv.
Sanoussi CN, Coscolla M, Ofori-Anyinam B, Otchere ID, Antonio M, Niemann S, Parkhill J, Harris S, Yeboah-Manu D, Gagneux S, Rigouts L, Affolabi D, de Jong BC, Meehan CJ. Sanoussi CN, et al. Among authors: meehan cj. Microb Genom. 2021 Jul;7(7):000437. doi: 10.1099/mgen.0.000437. Microb Genom. 2021. PMID: 34241588 Free PMC article.
Phylogenomics of Mycobacterium africanum reveals a new lineage and a complex evolutionary history.
Coscolla M, Gagneux S, Menardo F, Loiseau C, Ruiz-Rodriguez P, Borrell S, Otchere ID, Asante-Poku A, Asare P, Sánchez-Busó L, Gehre F, Sanoussi CN, Antonio M, Affolabi D, Fyfe J, Beckert P, Niemann S, Alabi AS, Grobusch MP, Kobbe R, Parkhill J, Beisel C, Fenner L, Böttger EC, Meehan CJ, Harris SR, de Jong BC, Yeboah-Manu D, Brites D. Coscolla M, et al. Among authors: meehan cj. Microb Genom. 2021 Feb;7(2):000477. doi: 10.1099/mgen.0.000477. Microb Genom. 2021. PMID: 33555243 Free PMC article.
Comparative genomics of Mycobacterium africanum Lineage 5 and Lineage 6 from Ghana suggests distinct ecological niches.
Otchere ID, Coscollá M, Sánchez-Busó L, Asante-Poku A, Brites D, Loiseau C, Meehan C, Osei-Wusu S, Forson A, Laryea C, Yahayah AI, Baddoo A, Ansa GA, Aboagye SY, Asare P, Borrell S, Gehre F, Beckert P, Kohl TA, N'dira S, Beisel C, Antonio M, Niemann S, de Jong BC, Parkhill J, Harris SR, Gagneux S, Yeboah-Manu D. Otchere ID, et al. Sci Rep. 2018 Jul 26;8(1):11269. doi: 10.1038/s41598-018-29620-2. Sci Rep. 2018. PMID: 30050166 Free PMC article.
Comparative genomics shows differences in the electron transport and carbon metabolic pathways of Mycobacterium africanum relative to Mycobacterium tuberculosis and suggests an adaptation to low oxygen tension.
Ofori-Anyinam B, Riley AJ, Jobarteh T, Gitteh E, Sarr B, Faal-Jawara TI, Rigouts L, Senghore M, Kehinde A, Onyejepu N, Antonio M, de Jong BC, Gehre F, Meehan CJ. Ofori-Anyinam B, et al. Among authors: meehan cj. Tuberculosis (Edinb). 2020 Jan;120:101899. doi: 10.1016/j.tube.2020.101899. Epub 2020 Jan 8. Tuberculosis (Edinb). 2020. PMID: 32090860 Free PMC article.
Whole genome sequence of Mycobacterium kansasii isolates of the genotype 1 from Brazilian patients with pulmonary disease demonstrates considerable heterogeneity.
Machado E, Vasconcellos SEG, Cerdeira C, Gomes LL, Junqueira R, Carvalho LD, Ramos JP, Redner P, Campos CED, Caldas PCS, Gomes APCS, Goldenberg T, Montes FF, Mello FCQ, Mussi VO, Lasunskaia E, Soolingen DV, Miranda AB, Rigouts L, Jong BC, Meehan CJ, Catanho M, Suffys PN. Machado E, et al. Among authors: meehan cj. Mem Inst Oswaldo Cruz. 2018 Jun 25;113(9):e180085. doi: 10.1590/0074-02760180085. Mem Inst Oswaldo Cruz. 2018. PMID: 29947722 Free PMC article.
Significant under expression of the DosR regulon in M. tuberculosis complex lineage 6 in sputum.
Ofori-Anyinam B, Dolganov G, Van T, Davis JL, Walter ND, Garcia BJ, Voskuil M, Fissette K, Diels M, Driesen M, Meehan CJ, Yeboah-Manu D, Coscolla M, Gagneux S, Antonio M, Schoolnik G, Gehre F, de Jong BC. Ofori-Anyinam B, et al. Among authors: meehan cj. Tuberculosis (Edinb). 2017 May;104:58-64. doi: 10.1016/j.tube.2017.03.001. Epub 2017 Mar 4. Tuberculosis (Edinb). 2017. PMID: 28454650 Free PMC article.
Whole genome sequencing of Mycobacterium tuberculosis: current standards and open issues.
Meehan CJ, Goig GA, Kohl TA, Verboven L, Dippenaar A, Ezewudo M, Farhat MR, Guthrie JL, Laukens K, Miotto P, Ofori-Anyinam B, Dreyer V, Supply P, Suresh A, Utpatel C, van Soolingen D, Zhou Y, Ashton PM, Brites D, Cabibbe AM, de Jong BC, de Vos M, Menardo F, Gagneux S, Gao Q, Heupink TH, Liu Q, Loiseau C, Rigouts L, Rodwell TC, Tagliani E, Walker TM, Warren RM, Zhao Y, Zignol M, Schito M, Gardy J, Cirillo DM, Niemann S, Comas I, Van Rie A. Meehan CJ, et al. Nat Rev Microbiol. 2019 Sep;17(9):533-545. doi: 10.1038/s41579-019-0214-5. Nat Rev Microbiol. 2019. PMID: 31209399 Review.
108 results