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Page 1
TRPC6, a therapeutic target for pulmonary hypertension.
Jain PP, Lai N, Xiong M, Chen J, Babicheva A, Zhao T, Parmisano S, Zhao M, Paquin C, Matti M, Powers R, Balistrieri A, Kim NH, Valdez-Jasso D, Thistlethwaite PA, Shyy JY, Wang J, Garcia JGN, Makino A, Yuan JX. Jain PP, et al. Among authors: valdez jasso d. Am J Physiol Lung Cell Mol Physiol. 2021 Dec 1;321(6):L1161-L1182. doi: 10.1152/ajplung.00159.2021. Epub 2021 Oct 27. Am J Physiol Lung Cell Mol Physiol. 2021. PMID: 34704831 Free PMC article.
Nicotinamide Phosphoribosyltransferase Promotes Pulmonary Vascular Remodeling and Is a Therapeutic Target in Pulmonary Arterial Hypertension.
Chen J, Sysol JR, Singla S, Zhao S, Yamamura A, Valdez-Jasso D, Abbasi T, Shioura KM, Sahni S, Reddy V, Sridhar A, Gao H, Torres J, Camp SM, Tang H, Ye SQ, Comhair S, Dweik R, Hassoun P, Yuan JX, Garcia JGN, Machado RF. Chen J, et al. Circulation. 2017 Apr 18;135(16):1532-1546. doi: 10.1161/CIRCULATIONAHA.116.024557. Epub 2017 Feb 15. Circulation. 2017. PMID: 28202489 Free PMC article.
Revisiting the mechanism of hypoxic pulmonary vasoconstriction using isolated perfused/ventilated mouse lung.
Jain PP, Hosokawa S, Xiong M, Babicheva A, Zhao T, Rodriguez M, Rahimi S, Pourhashemi K, Balistrieri F, Lai N, Malhotra A, Shyy JY, Valdez-Jasso D, Thistlethwaite PA, Makino A, Yuan JX. Jain PP, et al. Pulm Circ. 2020 Nov 25;10(4):2045894020956592. doi: 10.1177/2045894020956592. eCollection 2020 Oct-Dec. Pulm Circ. 2020. PMID: 33282184 Free PMC article.
Endothelial platelet-derived growth factor-mediated activation of smooth muscle platelet-derived growth factor receptors in pulmonary arterial hypertension.
Wu K, Tang H, Lin R, Carr SG, Wang Z, Babicheva A, Ayon RJ, Jain PP, Xiong M, Rodriguez M, Rahimi S, Balistrieri F, Rahimi S, Valdez-Jasso D, Simonson TS, Desai AA, Garcia JGN, Shyy JY, Thistlethwaite PA, Wang J, Makino A, Yuan JX. Wu K, et al. Pulm Circ. 2020 Sep 10;10(3):2045894020948470. doi: 10.1177/2045894020948470. eCollection 2020 Jul-Sep. Pulm Circ. 2020. PMID: 33294172 Free PMC article.
Halofuginone, a promising drug for treatment of pulmonary hypertension.
Jain PP, Zhao T, Xiong M, Song S, Lai N, Zheng Q, Chen J, Carr SG, Babicheva A, Izadi A, Rodriguez M, Rahimi S, Balistrieri F, Rahimi S, Simonson T, Valdez-Jasso D, Thistlethwaite PA, Shyy JY, Wang J, Makino A, Yuan JX. Jain PP, et al. Br J Pharmacol. 2021 Sep;178(17):3373-3394. doi: 10.1111/bph.15442. Epub 2021 Jul 31. Br J Pharmacol. 2021. PMID: 33694155 Free PMC article.
Upregulation of Calcium Homeostasis Modulators in Contractile-To-Proliferative Phenotypical Transition of Pulmonary Arterial Smooth Muscle Cells.
Rodriguez M, Chen J, Jain PP, Babicheva A, Xiong M, Li J, Lai N, Zhao T, Hernandez M, Balistrieri A, Parmisano S, Simonson T, Breen E, Valdez-Jasso D, Thistlethwaite PA, Shyy JY, Wang J, Garcia JGN, Makino A, Yuan JX. Rodriguez M, et al. Among authors: valdez jasso d. Front Physiol. 2021 Aug 2;12:714785. doi: 10.3389/fphys.2021.714785. eCollection 2021. Front Physiol. 2021. PMID: 34408668 Free PMC article.
Endothelial upregulation of mechanosensitive channel Piezo1 in pulmonary hypertension.
Wang Z, Chen J, Babicheva A, Jain PP, Rodriguez M, Ayon RJ, Ravellette KS, Wu L, Balistrieri F, Tang H, Wu X, Zhao T, Black SM, Desai AA, Garcia JGN, Sun X, Shyy JY, Valdez-Jasso D, Thistlethwaite PA, Makino A, Wang J, Yuan JX. Wang Z, et al. Among authors: valdez jasso d. Am J Physiol Cell Physiol. 2021 Dec 1;321(6):C1010-C1027. doi: 10.1152/ajpcell.00147.2021. Epub 2021 Oct 20. Am J Physiol Cell Physiol. 2021. PMID: 34669509 Free PMC article.
Cellular mechanosignaling in pulmonary arterial hypertension.
Wang A, Valdez-Jasso D. Wang A, et al. Among authors: valdez jasso d. Biophys Rev. 2021 Sep 2;13(5):747-756. doi: 10.1007/s12551-021-00828-3. eCollection 2021 Oct. Biophys Rev. 2021. PMID: 34765048 Free PMC article. Review.
Sphingosine Kinase 1 Deficiency in Smooth Muscle Cells Protects against Hypoxia-Mediated Pulmonary Hypertension via YAP1 Signaling.
Chen J, Lockett A, Zhao S, Huang LS, Wang Y, Wu W, Tang M, Haider S, Velez Rendon D, Khan R, Liu B, Felesena N, Sysol JR, Valdez-Jasso D, Tang H, Bai Y, Natarajan V, Machado RF. Chen J, et al. Among authors: valdez jasso d. Int J Mol Sci. 2022 Nov 22;23(23):14516. doi: 10.3390/ijms232314516. Int J Mol Sci. 2022. PMID: 36498853 Free PMC article.
27 results