Hofmann B - Search Results

1

Borcalein: a Carborane-Based Analogue of Baicalein with 12-Lipoxygenase-Independent Toxicity.

Kuhnert R, Kuhnert L, Sárosi MB, George S, Draca D, Paskas S, Hofmann B, Steinhilber D, Honscha W, Mijatović S, Maksimović-Ivanić D, Hey-Hawkins E. Kuhnert R, et al. Among authors: hofmann b. ChemMedChem. 2022 Jan 5;17(1):e202100588. doi: 10.1002/cmdc.202100588. Epub 2021 Nov 11. ChemMedChem. 2022. PMID: 34694057 Free PMC article.

2

CarbORev-5901: The First Carborane-Based Inhibitor of the 5-Lipoxygenase Pathway.

Kuhnert R, Sárosi MB, George S, Lönnecke P, Hofmann B, Steinhilber D, Murganic B, Mijatovic S, Maksimovic-Ivanic D, Hey-Hawkins E. Kuhnert R, et al. Among authors: hofmann b. ChemMedChem. 2017 Jul 6;12(13):1081-1086. doi: 10.1002/cmdc.201700309. Epub 2017 Jun 21. ChemMedChem. 2017. PMID: 28569429

3

Carborane-Based Analogues of 5-Lipoxygenase Inhibitors Co-inhibit Heat Shock Protein 90 in HCT116 Cells.

Kuhnert R, Sárosi MB, George S, Lönnecke P, Hofmann B, Steinhilber D, Steinmann S, Schneider-Stock R, Murganić B, Mijatović S, Maksimović-Ivanić D, Hey-Hawkins E. Kuhnert R, et al. Among authors: hofmann b. ChemMedChem. 2019 Jan 22;14(2):255-261. doi: 10.1002/cmdc.201800651. Epub 2018 Dec 21. ChemMedChem. 2019. PMID: 30471171

4

Potent inhibitors of 5-lipoxygenase identified using pseudoreceptors.

Rödl CB, Tanrikulu Y, Wisniewska JM, Proschak E, Schneider G, Steinhilber D, Hofmann B. Rödl CB, et al. Among authors: hofmann b. ChemMedChem. 2011 Jun 6;6(6):1001-5. doi: 10.1002/cmdc.201100059. Epub 2011 Apr 19. ChemMedChem. 2011. PMID: 21506275 No abstract available.

5

5-Lipoxygenase inhibitors: a review of recent patents (2010-2012).

Hofmann B, Steinhilber D. Hofmann B, et al. Expert Opin Ther Pat. 2013 Jul;23(7):895-909. doi: 10.1517/13543776.2013.791678. Epub 2013 Apr 21. Expert Opin Ther Pat. 2013. PMID: 23600432 Review.

6

Recent advances in the search for novel 5-lipoxygenase inhibitors.

Steinhilber D, Hofmann B. Steinhilber D, et al. Among authors: hofmann b. Basic Clin Pharmacol Toxicol. 2014 Jan;114(1):70-7. doi: 10.1111/bcpt.12114. Epub 2013 Sep 18. Basic Clin Pharmacol Toxicol. 2014. PMID: 23953428 Free article. Review.

7

Scaffold-hopping cascade yields potent inhibitors of 5-lipoxygenase.

Hofmann B, Franke L, Proschak E, Tanrikulu Y, Schneider P, Steinhilber D, Schneider G. Hofmann B, et al. ChemMedChem. 2008 Oct;3(10):1535-8. doi: 10.1002/cmdc.200800153. ChemMedChem. 2008. PMID: 18688907 No abstract available.

8

Synthesis and biological evaluation of a class of 5-benzylidene-2-phenyl-thiazolinones as potent 5-lipoxygenase inhibitors.

Barzen S, Rödl CB, Lill A, Steinhilber D, Stark H, Hofmann B. Barzen S, et al. Among authors: hofmann b. Bioorg Med Chem. 2012 Jun 1;20(11):3575-83. doi: 10.1016/j.bmc.2012.04.003. Epub 2012 Apr 11. Bioorg Med Chem. 2012. PMID: 22551629

9

Development and evaluation of ST-1829 based on 5-benzylidene-2-phenylthiazolones as promising agent for anti-leukotriene therapy.

Lill AP, Rödl CB, Steinhilber D, Stark H, Hofmann B. Lill AP, et al. Among authors: hofmann b. Eur J Med Chem. 2015 Jan 7;89:503-23. doi: 10.1016/j.ejmech.2014.10.054. Epub 2014 Oct 18. Eur J Med Chem. 2015. PMID: 25462262

10

Identification and Characterization of a New Protein Isoform of Human 5-Lipoxygenase.

Häfner AK, Beilstein K, Graab P, Ball AK, Saul MJ, Hofmann B, Steinhilber D. Häfner AK, et al. Among authors: hofmann b. PLoS One. 2016 Nov 17;11(11):e0166591. doi: 10.1371/journal.pone.0166591. eCollection 2016. PLoS One. 2016. PMID: 27855198 Free PMC article.

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