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Mucosal transcriptomics highlight lncRNAs implicated in ulcerative colitis, Crohn's disease, and celiac disease.
Braun T, Sosnovski KE, Amir A, BenShoshan M, VanDussen KL, Karns R, Levhar N, Abbas-Egbariya H, Hadar R, Efroni G, Castel D, Avivi C, Rosen MJ, Grifiths AM, Walters TD, Mack DR, Boyle BM, Ali SA, Moore SR, Schirmer M, Xavier RJ, Kugathasan S, Jegga AG, Weiss B, Mayer C, Barshack I, Ben-Horin S, Ulitsky I, Beucher A, Ferrer J, Hyams JS, Denson LA, Haberman Y. Braun T, et al. Among authors: karns r. JCI Insight. 2023 Jul 24;8(14):e170181. doi: 10.1172/jci.insight.170181. JCI Insight. 2023. PMID: 37261910 Free PMC article.
Thermoneutral housing exacerbates nonalcoholic fatty liver disease in mice and allows for sex-independent disease modeling.
Giles DA, Moreno-Fernandez ME, Stankiewicz TE, Graspeuntner S, Cappelletti M, Wu D, Mukherjee R, Chan CC, Lawson MJ, Klarquist J, Sünderhauf A, Softic S, Kahn CR, Stemmer K, Iwakura Y, Aronow BJ, Karns R, Steinbrecher KA, Karp CL, Sheridan R, Shanmukhappa SK, Reynaud D, Haslam DB, Sina C, Rupp J, Hogan SP, Divanovic S. Giles DA, et al. Among authors: karns r. Nat Med. 2017 Jul;23(7):829-838. doi: 10.1038/nm.4346. Epub 2017 Jun 12. Nat Med. 2017. PMID: 28604704 Free PMC article.
Microbiota-sensitive epigenetic signature predicts inflammation in Crohn's disease.
Kelly D, Kotliar M, Woo V, Jagannathan S, Whitt J, Moncivaiz J, Aronow BJ, Dubinsky MC, Hyams JS, Markowitz JF, Baldassano RN, Stephens MC, Walters TD, Kugathasan S, Haberman Y, Sundaram N, Rosen MJ, Helmrath M, Karns R, Barski A, Denson LA, Alenghat T. Kelly D, et al. Among authors: karns r. JCI Insight. 2018 Sep 20;3(18):e122104. doi: 10.1172/jci.insight.122104. eCollection 2018 Sep 20. JCI Insight. 2018. PMID: 30232290 Free PMC article.
Constitutive STAT5 activation regulates Paneth and Paneth-like cells to control Clostridium difficile colitis.
Liu R, Moriggl R, Zhang D, Li H, Karns R, Ruan HB, Niu H, Mayhew C, Watson C, Bangar H, Cha SW, Haslam D, Zhang T, Gilbert S, Li N, Helmrath M, Wells J, Denson L, Han X. Liu R, et al. Among authors: karns r. Life Sci Alliance. 2019 Apr 4;2(2):e201900296. doi: 10.26508/lsa.201900296. Print 2019 Apr. Life Sci Alliance. 2019. PMID: 30948494 Free PMC article.
Microbiota-derived metabolite promotes HDAC3 activity in the gut.
Wu SE, Hashimoto-Hill S, Woo V, Eshleman EM, Whitt J, Engleman L, Karns R, Denson LA, Haslam DB, Alenghat T. Wu SE, et al. Among authors: karns r. Nature. 2020 Oct;586(7827):108-112. doi: 10.1038/s41586-020-2604-2. Epub 2020 Jul 30. Nature. 2020. PMID: 32731255 Free PMC article.
Canonical Wnt Signaling Ameliorates Aging of Intestinal Stem Cells.
Nalapareddy K, Nattamai KJ, Kumar RS, Karns R, Wikenheiser-Brokamp KA, Sampson LL, Mahe MM, Sundaram N, Yacyshyn MB, Yacyshyn B, Helmrath MA, Zheng Y, Geiger H. Nalapareddy K, et al. Among authors: karns r. Cell Rep. 2017 Mar 14;18(11):2608-2621. doi: 10.1016/j.celrep.2017.02.056. Cell Rep. 2017. PMID: 28297666 Free PMC article.
Type I interferon sensing unlocks dormant adipocyte inflammatory potential.
Chan CC, Damen MSMA, Moreno-Fernandez ME, Stankiewicz TE, Cappelletti M, Alarcon PC, Oates JR, Doll JR, Mukherjee R, Chen X, Karns R, Weirauch MT, Helmrath MA, Inge TH, Divanovic S. Chan CC, et al. Among authors: karns r. Nat Commun. 2020 Jun 2;11(1):2745. doi: 10.1038/s41467-020-16571-4. Nat Commun. 2020. PMID: 32488081 Free PMC article.
Type I interferons regulate susceptibility to inflammation-induced preterm birth.
Cappelletti M, Presicce P, Lawson MJ, Chaturvedi V, Stankiewicz TE, Vanoni S, Harley IT, McAlees JW, Giles DA, Moreno-Fernandez ME, Rueda CM, Senthamaraikannan P, Sun X, Karns R, Hoebe K, Janssen EM, Karp CL, Hildeman DA, Hogan SP, Kallapur SG, Chougnet CA, Way SS, Divanovic S. Cappelletti M, et al. Among authors: karns r. JCI Insight. 2017 Mar 9;2(5):e91288. doi: 10.1172/jci.insight.91288. JCI Insight. 2017. PMID: 28289719 Free PMC article.
Erratum: Thermoneutral housing exacerbates nonalcoholic fatty liver disease in mice and allows for sex-independent disease modeling.
Giles DA, Moreno-Fernandez ME, Stankiewicz TE, Graspeuntner S, Cappelletti M, Wu D, Mukherjee R, Chan CC, Lawson MJ, Klarquist J, Sünderhauf A, Softic S, Kahn CR, Stemmer K, Iwakura Y, Aronow BJ, Karns R, Steinbrecher KA, Karp CL, Sheridan R, Shanmukhappa SK, Reynaud D, Haslam DB, Sina C, Rupp J, Hogan SP, Divanovic S. Giles DA, et al. Among authors: karns r. Nat Med. 2017 Oct 6;23(10):1241. doi: 10.1038/nm1017-1241c. Nat Med. 2017. PMID: 28985207
96 results