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GAK and PRKCD are positive regulators of PRKN-independent mitophagy.
Munson MJ, Mathai BJ, Ng MYW, Trachsel-Moncho L, de la Ballina LR, Schultz SW, Aman Y, Lystad AH, Singh S, Singh S, Wesche J, Fang EF, Simonsen A. Munson MJ, et al. Among authors: simonsen a. Nat Commun. 2021 Oct 20;12(1):6101. doi: 10.1038/s41467-021-26331-7. Nat Commun. 2021. PMID: 34671015 Free PMC article.
Assays to monitor aggrephagy.
Lystad AH, Simonsen A. Lystad AH, et al. Among authors: simonsen a. Methods. 2015 Mar;75:112-9. doi: 10.1016/j.ymeth.2014.12.019. Epub 2014 Dec 31. Methods. 2015. PMID: 25555675
Deubiquitinase inhibition by WP1130 leads to ULK1 aggregation and blockade of autophagy.
Drießen S, Berleth N, Friesen O, Löffler AS, Böhler P, Hieke N, Stuhldreier F, Peter C, Schink KO, Schultz SW, Stenmark H, Holland P, Simonsen A, Wesselborg S, Stork B. Drießen S, et al. Among authors: simonsen a. Autophagy. 2015;11(9):1458-70. doi: 10.1080/15548627.2015.1067359. Autophagy. 2015. PMID: 26207339 Free PMC article.
Phosphoinositide-binding proteins in autophagy.
Lystad AH, Simonsen A. Lystad AH, et al. Among authors: simonsen a. FEBS Lett. 2016 Aug;590(15):2454-68. doi: 10.1002/1873-3468.12286. Epub 2016 Jul 23. FEBS Lett. 2016. PMID: 27391591 Free article. Review.
HS1BP3 negatively regulates autophagy by modulation of phosphatidic acid levels.
Holland P, Knævelsrud H, Søreng K, Mathai BJ, Lystad AH, Pankiv S, Bjørndal GT, Schultz SW, Lobert VH, Chan RB, Zhou B, Liestøl K, Carlsson SR, Melia TJ, Di Paolo G, Simonsen A. Holland P, et al. Among authors: simonsen a. Nat Commun. 2016 Dec 22;7:13889. doi: 10.1038/ncomms13889. Nat Commun. 2016. PMID: 28004827 Free PMC article.
Studying Autophagy in Zebrafish.
Mathai BJ, Meijer AH, Simonsen A. Mathai BJ, et al. Among authors: simonsen a. Cells. 2017 Jul 9;6(3):21. doi: 10.3390/cells6030021. Cells. 2017. PMID: 28698482 Free PMC article. Review.
442 results