De Luca L - Search Results

1

Exploration of the 2,3-dihydroisoindole pharmacophore for inhibition of the influenza virus PA endonuclease.

Rogolino D, Naesens L, Bartoli J, Carcelli M, De Luca L, Pelosi G, Stokes RW, Van Berwaer R, Vittorio S, Stevaert A, Cohen SM. Rogolino D, et al. Among authors: de luca l. Bioorg Chem. 2021 Nov;116:105388. doi: 10.1016/j.bioorg.2021.105388. Epub 2021 Oct 1. Bioorg Chem. 2021. PMID: 34670331 Free PMC article.

2

Discovery of 2,3-diaryl-1,3-thiazolidin-4-ones as potent anti-HIV-1 agents.

Barreca ML, Chimirri A, De Luca L, Monforte AM, Monforte P, Rao A, Zappalà M, Balzarini J, De Clercq E, Pannecouque C, Witvrouw M. Barreca ML, et al. Among authors: de luca l, de clercq e. Bioorg Med Chem Lett. 2001 Jul 9;11(13):1793-6. doi: 10.1016/s0960-894x(01)00304-3. Bioorg Med Chem Lett. 2001. PMID: 11425562

3

Design, synthesis, structure-activity relationships, and molecular modeling studies of 2,3-diaryl-1,3-thiazolidin-4-ones as potent anti-HIV agents.

Barreca ML, Balzarini J, Chimirri A, De Clercq E, De Luca L, Höltje HD, Höltje M, Monforte AM, Monforte P, Pannecouque C, Rao A, Zappalà M. Barreca ML, et al. Among authors: de luca l, de clercq e. J Med Chem. 2002 Nov 21;45(24):5410-3. doi: 10.1021/jm020977+. J Med Chem. 2002. PMID: 12431069

4

Computational strategies in discovering novel non-nucleoside inhibitors of HIV-1 RT.

Barreca ML, Rao A, De Luca L, Zappalà M, Monforte AM, Maga G, Pannecouque C, Balzarini J, De Clercq E, Chimirri A, Monforte P. Barreca ML, et al. Among authors: de luca l, de clercq e. J Med Chem. 2005 May 5;48(9):3433-7. doi: 10.1021/jm049279a. J Med Chem. 2005. PMID: 15857150

5

Pharmacophore-based design of HIV-1 integrase strand-transfer inhibitors.

Barreca ML, Ferro S, Rao A, De Luca L, Zappalà M, Monforte AM, Debyser Z, Witvrouw M, Chimirri A. Barreca ML, et al. Among authors: de luca l. J Med Chem. 2005 Nov 3;48(22):7084-8. doi: 10.1021/jm050549e. J Med Chem. 2005. PMID: 16250669

6

Discovery of novel benzimidazolones as potent non-nucleoside reverse transcriptase inhibitors active against wild-type and mutant HIV-1 strains.

Barreca ML, Rao A, De Luca L, Iraci N, Monforte AM, Maga G, De Clercq E, Pannecouque C, Balzarini J, Chimirri A. Barreca ML, et al. Among authors: de luca l, de clercq e. Bioorg Med Chem Lett. 2007 Apr 1;17(7):1956-60. doi: 10.1016/j.bmcl.2007.01.025. Epub 2007 Jan 19. Bioorg Med Chem Lett. 2007. PMID: 17276064

7

Synthesis, resolution, stereochemistry, and molecular modeling of (R)- and (S)-2-acetyl-1-(4'-chlorophenyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline AMPAR antagonists.

Gitto R, Ficarra R, Stancanelli R, Guardo M, De Luca L, Barreca ML, Pagano B, Rotondo A, Bruno G, Russo E, De Sarro G, Chimirri A. Gitto R, et al. Among authors: de luca l, de sarro g. Bioorg Med Chem. 2007 Aug 15;15(16):5417-23. doi: 10.1016/j.bmc.2007.05.059. Epub 2007 May 31. Bioorg Med Chem. 2007. PMID: 17566746

8

Synthesis and anticonvulsant evaluation of N-substituted isoquinoline AMPA receptor antagonists.

Gitto R, De Luca L, Pagano B, Citraro R, De Sarro G, Costa L, Ciranna L, Chimirri A. Gitto R, et al. Among authors: de luca l, de sarro g. Bioorg Med Chem. 2008 Mar 1;16(5):2379-84. doi: 10.1016/j.bmc.2007.11.071. Epub 2007 Nov 29. Bioorg Med Chem. 2008. PMID: 18077172

9

A refined pharmacophore model for HIV-1 integrase inhibitors: Optimization of potency in the 1H-benzylindole series.

De Luca L, Barreca ML, Ferro S, Iraci N, Michiels M, Christ F, Debyser Z, Witvrouw M, Chimirri A. De Luca L, et al. Bioorg Med Chem Lett. 2008 May 1;18(9):2891-5. doi: 10.1016/j.bmcl.2008.03.089. Epub 2008 Apr 8. Bioorg Med Chem Lett. 2008. PMID: 18417342

10

Novel N1-substituted 1,3-dihydro-2H-benzimidazol-2-ones as potent non-nucleoside reverse transcriptase inhibitors.

Monforte AM, Rao A, Logoteta P, Ferro S, De Luca L, Barreca ML, Iraci N, Maga G, De Clercq E, Pannecouque C, Chimirri A. Monforte AM, et al. Among authors: de luca l, de clercq e. Bioorg Med Chem. 2008 Aug 1;16(15):7429-35. doi: 10.1016/j.bmc.2008.06.012. Epub 2008 Jun 13. Bioorg Med Chem. 2008. PMID: 18585918

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