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Disrupting D1-NMDA or D2-NMDA receptor heteromerization prevents cocaine's rewarding effects but preserves natural reward processing.
Andrianarivelo A, Saint-Jour E, Pousinha P, Fernandez SP, Petitbon A, De Smedt-Peyrusse V, Heck N, Ortiz V, Allichon MC, Kappès V, Betuing S, Walle R, Zhu Y, Joséphine C, Bemelmans AP, Turecki G, Mechawar N, Javitch JA, Caboche J, Trifilieff P, Barik J, Vanhoutte P. Andrianarivelo A, et al. Among authors: kappes v. Sci Adv. 2021 Oct 22;7(43):eabg5970. doi: 10.1126/sciadv.abg5970. Epub 2021 Oct 20. Sci Adv. 2021. PMID: 34669474 Free PMC article.
Endocytosis controls glutamate-induced nuclear accumulation of ERK.
Trifilieff P, Lavaur J, Pascoli V, Kappès V, Brami-Cherrier K, Pagès C, Micheau J, Caboche J, Vanhoutte P. Trifilieff P, et al. Among authors: kappes v. Mol Cell Neurosci. 2009 Jul;41(3):325-36. doi: 10.1016/j.mcn.2009.04.006. Epub 2009 May 3. Mol Cell Neurosci. 2009. PMID: 19398002
Activity-Regulated Cytoskeleton-Associated Protein Accumulates in the Nucleus in Response to Cocaine and Acts as a Brake on Chromatin Remodeling and Long-Term Behavioral Alterations.
Salery M, Dos Santos M, Saint-Jour E, Moumné L, Pagès C, Kappès V, Parnaudeau S, Caboche J, Vanhoutte P. Salery M, et al. Among authors: kappes v. Biol Psychiatry. 2017 Apr 1;81(7):573-584. doi: 10.1016/j.biopsych.2016.05.025. Epub 2016 Jun 16. Biol Psychiatry. 2017. PMID: 27567310 Free article.
Early epigenomic and transcriptional changes reveal Elk-1 transcription factor as a therapeutic target in Huntington's disease.
Yildirim F, Ng CW, Kappes V, Ehrenberger T, Rigby SK, Stivanello V, Gipson TA, Soltis AR, Vanhoutte P, Caboche J, Housman DE, Fraenkel E. Yildirim F, et al. Among authors: kappes v. Proc Natl Acad Sci U S A. 2019 Dec 3;116(49):24840-24851. doi: 10.1073/pnas.1908113116. Epub 2019 Nov 19. Proc Natl Acad Sci U S A. 2019. PMID: 31744868 Free PMC article.
Cell-type- and region-specific modulation of cocaine seeking by micro-RNA-1 in striatal projection neurons.
Forget B, Garcia EM, Godino A, Rodriguez LD, Kappes V, Poirier P, Andrianarivelo A, Marchan ES, Allichon MC, Marias M, Vanhoutte P, Girault JA, Maldonado R, Caboche J. Forget B, et al. Among authors: kappes v. Mol Psychiatry. 2022 Feb;27(2):918-928. doi: 10.1038/s41380-021-01328-2. Epub 2021 Nov 16. Mol Psychiatry. 2022. PMID: 34785784 Free PMC article.
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