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Electrophysiological and Proarrhythmic Effects of Hydroxychloroquine Challenge in Guinea-Pig Hearts.
Wang G, Lu CJ, Trafford AW, Tian X, Flores HM, Maj P, Zhang K, Niu Y, Wang L, Du Y, Ji X, Xu Y, Wu L, Li D, Herring N, Paterson D, Huang CL, Zhang H, Lei M, Hao G. Wang G, et al. Among authors: zhang k, zhang h. ACS Pharmacol Transl Sci. 2021 Aug 30;4(5):1639-1653. doi: 10.1021/acsptsci.1c00166. eCollection 2021 Oct 8. ACS Pharmacol Transl Sci. 2021. PMID: 34661080 Free PMC article.
SCN5A and sinoatrial node pacemaker function.
Lei M, Zhang H, Grace AA, Huang CL. Lei M, et al. Among authors: zhang h. Cardiovasc Res. 2007 Jun 1;74(3):356-65. doi: 10.1016/j.cardiores.2007.01.009. Epub 2007 Jan 19. Cardiovasc Res. 2007. PMID: 17368591 Review.
Mitogen-activated protein kinase kinase 4 deficiency in cardiomyocytes causes connexin 43 reduction and couples hypertrophic signals to ventricular arrhythmogenesis.
Zi M, Kimura TE, Liu W, Jin J, Higham J, Kharche S, Hao G, Shi Y, Shen W, Prehar S, Mironov A, Neyses L, Bierhuizen MF, Boyett MR, Zhang H, Lei M, Cartwright EJ, Wang X. Zi M, et al. Among authors: zhang h. J Biol Chem. 2011 May 20;286(20):17821-30. doi: 10.1074/jbc.M111.228791. Epub 2011 Mar 28. J Biol Chem. 2011. PMID: 21454599 Free PMC article. No abstract available.
TGF-β1-mediated fibrosis and ion channel remodeling are key mechanisms in producing the sinus node dysfunction associated with SCN5A deficiency and aging.
Hao X, Zhang Y, Zhang X, Nirmalan M, Davies L, Konstantinou D, Yin F, Dobrzynski H, Wang X, Grace A, Zhang H, Boyett M, Huang CL, Lei M. Hao X, et al. Among authors: zhang x, zhang h, zhang y. Circ Arrhythm Electrophysiol. 2011 Jun;4(3):397-406. doi: 10.1161/CIRCEP.110.960807. Epub 2011 Apr 14. Circ Arrhythm Electrophysiol. 2011. PMID: 21493874
Altered sinoatrial node function and intra-atrial conduction in murine gain-of-function Scn5a+/ΔKPQ hearts suggest an overlap syndrome.
Wu J, Zhang Y, Zhang X, Cheng L, Lammers WJ, Grace AA, Fraser JA, Zhang H, Huang CL, Lei M. Wu J, et al. Among authors: zhang x, zhang h, zhang y. Am J Physiol Heart Circ Physiol. 2012 Apr 1;302(7):H1510-23. doi: 10.1152/ajpheart.00357.2011. Epub 2012 Jan 27. Am J Physiol Heart Circ Physiol. 2012. PMID: 22287583 Free PMC article.
Mkk4 is a negative regulator of the transforming growth factor beta 1 signaling associated with atrial remodeling and arrhythmogenesis with age.
Davies L, Jin J, Shen W, Tsui H, Shi Y, Wang Y, Zhang Y, Hao G, Wu J, Chen S, Fraser JA, Dong N, Christoffels V, Ravens U, Huang CL, Zhang H, Cartwright EJ, Wang X, Lei M. Davies L, et al. Among authors: zhang h, zhang y. J Am Heart Assoc. 2014 Apr 10;3(2):e000340. doi: 10.1161/JAHA.113.000340. J Am Heart Assoc. 2014. PMID: 24721794 Free PMC article.
Optimal iodine staining of cardiac tissue for X-ray computed tomography.
Butters TD, Castro SJ, Lowe T, Zhang Y, Lei M, Withers PJ, Zhang H. Butters TD, et al. Among authors: zhang h, zhang y. PLoS One. 2014 Aug 29;9(8):e105552. doi: 10.1371/journal.pone.0105552. eCollection 2014. PLoS One. 2014. PMID: 25170844 Free PMC article.
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