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A covalent fragment-based strategy targeting a novel cysteine to inhibit activity of mutant EGFR kinase.
Kuki N, Walmsley DL, Kanai K, Takechi S, Yoshida M, Murakami R, Takano K, Tominaga Y, Takahashi M, Ito S, Nakao N, Angove H, Baker LM, Carter E, Dokurno P, Le Strat L, Macias AT, Molyneaux CA, Murray JB, Surgenor AE, Hamada T, Hubbard RE. Kuki N, et al. Among authors: le strat l. RSC Med Chem. 2023 Oct 19;14(12):2731-2737. doi: 10.1039/d3md00439b. eCollection 2023 Dec 13. RSC Med Chem. 2023. PMID: 38107172
Current Paradigm of Hepatitis E Virus Among Pediatric and Adult Patients.
Belei O, Ancusa O, Mara A, Olariu L, Amaricai E, Folescu R, Zamfir CL, Gurgus D, Motoc AG, Stânga LC, Strat L, Marginean O. Belei O, et al. Among authors: strat l. Front Pediatr. 2021 Sep 30;9:721918. doi: 10.3389/fped.2021.721918. eCollection 2021. Front Pediatr. 2021. PMID: 34660485 Free PMC article. Review.
Application of Off-Rate Screening in the Identification of Novel Pan-Isoform Inhibitors of Pyruvate Dehydrogenase Kinase.
Brough PA, Baker L, Bedford S, Brown K, Chavda S, Chell V, D'Alessandro J, Davies NG, Davis B, Le Strat L, Macias AT, Maddox D, Mahon PC, Massey AJ, Matassova N, McKenna S, Meissner JW, Moore JD, Murray JB, Northfield CJ, Parry C, Parsons R, Roughley SD, Shaw T, Simmonite H, Stokes S, Surgenor A, Stefaniak E, Robertson A, Wang Y, Webb P, Whitehead N, Wood M. Brough PA, et al. Among authors: le strat l. J Med Chem. 2017 Mar 23;60(6):2271-2286. doi: 10.1021/acs.jmedchem.6b01478. Epub 2017 Feb 15. J Med Chem. 2017. PMID: 28199108
[Reasons for conservative treatment in breast cancer].
Pricop M, Strat L, Muscă S, Negură A, Slătineanu S. Pricop M, et al. Among authors: strat l. Rev Med Chir Soc Med Nat Iasi. 2003 Jul-Sep;107(3):599-602. Rev Med Chir Soc Med Nat Iasi. 2003. PMID: 14756069 Romanian.
[Malignancy risk in some benign mammary lesions].
Muscă S, Strat L, Maxim R, Negură A, Florea A, Slătineanu S, Pricop M. Muscă S, et al. Among authors: strat l. Rev Med Chir Soc Med Nat Iasi. 2003 Apr-Jun;107(2):375-8. Rev Med Chir Soc Med Nat Iasi. 2003. PMID: 14755944 Romanian.
11 results