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523 results

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Page 1
Autophagy in mesenchymal progenitors protects mice against bone marrow failure after severe intermittent stress.
Landspersky T, Saçma M, Rivière J, Hecker JS, Hettler F, Hameister E, Brandstetter K, Istvánffy R, Romero Marquez S, Ludwig R, Götz M, Buck M, Wolf M, Schiemann M, Ruland J, Strunk D, Shimamura A, Myers K, Yamaguchi TP, Kieslinger M, Leonhardt H, Bassermann F, Götze KS, Geiger H, Schreck C, Oostendorp RAJ. Landspersky T, et al. Among authors: leonhardt h. Blood. 2022 Feb 3;139(5):690-703. doi: 10.1182/blood.2021011775. Blood. 2022. PMID: 34657154 Free PMC article.
Direct modulation of the bone marrow mesenchymal stromal cell compartment by azacitidine enhances healthy hematopoiesis.
Wenk C, Garz AK, Grath S, Huberle C, Witham D, Weickert M, Malinverni R, Niggemeyer J, Kyncl M, Hecker J, Pagel C, Mulholland CB, Müller-Thomas C, Leonhardt H, Bassermann F, Oostendorp RAJ, Metzeler KH, Buschbeck M, Götze KS. Wenk C, et al. Among authors: leonhardt h. Blood Adv. 2018 Dec 11;2(23):3447-3461. doi: 10.1182/bloodadvances.2018022053. Blood Adv. 2018. PMID: 30518537 Free PMC article.
Targeting FLT3 with a new-generation antibody-drug conjugate in combination with kinase inhibitors for treatment of AML.
Roas M, Vick B, Kasper MA, Able M, Polzer H, Gerlach M, Kremmer E, Hecker JS, Schmitt S, Stengl A, Waller V, Hohmann N, Festini M, Ludwig A, Rohrbacher L, Herold T, Subklewe M, Götze KS, Hackenberger CPR, Schumacher D, Helma-Smets J, Jeremias I, Leonhardt H, Spiekermann K. Roas M, et al. Among authors: leonhardt h. Blood. 2023 Mar 2;141(9):1023-1035. doi: 10.1182/blood.2021015246. Blood. 2023. PMID: 35981498 Free article.
Rad50-CARD9 interactions link cytosolic DNA sensing to IL-1β production.
Roth S, Rottach A, Lotz-Havla AS, Laux V, Muschaweckh A, Gersting SW, Muntau AC, Hopfner KP, Jin L, Vanness K, Petrini JH, Drexler I, Leonhardt H, Ruland J. Roth S, et al. Among authors: leonhardt h. Nat Immunol. 2014 Jun;15(6):538-45. doi: 10.1038/ni.2888. Epub 2014 Apr 28. Nat Immunol. 2014. PMID: 24777530 Free PMC article.
Cohesin depleted cells rebuild functional nuclear compartments after endomitosis.
Cremer M, Brandstetter K, Maiser A, Rao SSP, Schmid VJ, Guirao-Ortiz M, Mitra N, Mamberti S, Klein KN, Gilbert DM, Leonhardt H, Cardoso MC, Aiden EL, Harz H, Cremer T. Cremer M, et al. Among authors: leonhardt h. Nat Commun. 2020 Dec 1;11(1):6146. doi: 10.1038/s41467-020-19876-6. Nat Commun. 2020. PMID: 33262376 Free PMC article.
Differences in nanoscale organization of regulatory active and inactive human chromatin.
Brandstetter K, Zülske T, Ragoczy T, Hörl D, Guirao-Ortiz M, Steinek C, Barnes T, Stumberger G, Schwach J, Haugen E, Rynes E, Korber P, Stamatoyannopoulos JA, Leonhardt H, Wedemann G, Harz H. Brandstetter K, et al. Among authors: leonhardt h. Biophys J. 2022 Mar 15;121(6):977-990. doi: 10.1016/j.bpj.2022.02.009. Epub 2022 Feb 10. Biophys J. 2022. PMID: 35150617 Free PMC article.
Adapter CAR T cells to counteract T-cell exhaustion and enable flexible targeting in AML.
Nixdorf D, Sponheimer M, Berghammer D, Engert F, Bader U, Philipp N, Kazerani M, Straub T, Rohrbacher L, Wange L, Dapa S, Atar D, Seitz CM, Brandstetter K, Linder A, von Bergwelt M, Leonhardt H, Mittelstaet J, Kaiser A, Bücklein V, Subklewe M. Nixdorf D, et al. Among authors: leonhardt h. Leukemia. 2023 Jun;37(6):1298-1310. doi: 10.1038/s41375-023-01905-0. Epub 2023 Apr 27. Leukemia. 2023. PMID: 37106163 Free PMC article.
523 results