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Page 1
Preclinical characterization of [18F]T-008, a novel PET imaging radioligand for cholesterol 24-hydroxylase.
Koike T, Constantinescu CC, Ikeda S, Nishi T, Sunahara E, Miyamoto M, Cole P, Barret O, Alagille D, Papin C, Morley T, Fowles K, Seibyl J, Tamagnan G, Kuroita T. Koike T, et al. Among authors: morley t. Eur J Nucl Med Mol Imaging. 2022 Mar;49(4):1148-1156. doi: 10.1007/s00259-021-05565-z. Epub 2021 Oct 15. Eur J Nucl Med Mol Imaging. 2022. PMID: 34651220 Free PMC article.
Adenosine 2A receptor occupancy by tozadenant and preladenant in rhesus monkeys.
Barret O, Hannestad J, Alagille D, Vala C, Tavares A, Papin C, Morley T, Fowles K, Lee H, Seibyl J, Tytgat D, Laruelle M, Tamagnan G. Barret O, et al. Among authors: morley t. J Nucl Med. 2014 Oct;55(10):1712-8. doi: 10.2967/jnumed.114.142067. Epub 2014 Jul 31. J Nucl Med. 2014. PMID: 25082853 Free article.
Dopamine D1 Receptor Agonist PET Tracer Development: Assessment in Nonhuman Primates.
Barret O, Zhang L, Alagille D, Constantinescu CC, Sandiego C, Papin C, Sullivan JM, Morley T, Carroll VM, Seibyl J, Chen J, Lee C, Villalobos A, Gray D, McCarthy TJ, Tamagnan G. Barret O, et al. Among authors: morley t. J Nucl Med. 2021 Sep 1;62(9):1307-1313. doi: 10.2967/jnumed.120.256008. Epub 2021 Feb 12. J Nucl Med. 2021. PMID: 33579806 Free PMC article.
Design, Synthesis, and Evaluation of (2-Aminocyclopropyl)phenyl Derivatives as Novel Positron Emission Tomography Imaging Agents for Lysine-Specific Demethylase 1 in the Brain.
Hattori Y, Matsuda S, Baba R, Matsumiya K, Iwasaki S, Constantinescu CC, Morley TJ, Carroll VM, Papin C, Gouasmat A, Alagille D, Tamagnan G, Koike T. Hattori Y, et al. Among authors: morley tj. J Med Chem. 2021 Apr 8;64(7):3780-3793. doi: 10.1021/acs.jmedchem.0c01937. Epub 2021 Mar 17. J Med Chem. 2021. PMID: 33729758
Preclinical In Vitro and In Vivo Characterization of Synaptic Vesicle 2A-Targeting Compounds Amenable to F-18 Labeling as Potential PET Radioligands for Imaging of Synapse Integrity.
Patel S, Knight A, Krause S, Teceno T, Tresse C, Li S, Cai Z, Gouasmat A, Carroll VM, Barret O, Gottmukkala V, Zhang W, Xiang X, Morley T, Huang Y, Passchier J. Patel S, et al. Among authors: morley t. Mol Imaging Biol. 2020 Aug;22(4):832-841. doi: 10.1007/s11307-019-01428-0. Mol Imaging Biol. 2020. PMID: 31728839
202 results