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Preclinical characterization of [18F]T-008, a novel PET imaging radioligand for cholesterol 24-hydroxylase.
Koike T, Constantinescu CC, Ikeda S, Nishi T, Sunahara E, Miyamoto M, Cole P, Barret O, Alagille D, Papin C, Morley T, Fowles K, Seibyl J, Tamagnan G, Kuroita T. Koike T, et al. Among authors: constantinescu cc. Eur J Nucl Med Mol Imaging. 2022 Mar;49(4):1148-1156. doi: 10.1007/s00259-021-05565-z. Epub 2021 Oct 15. Eur J Nucl Med Mol Imaging. 2022. PMID: 34651220 Free PMC article.
Dopamine D1 Receptor Agonist PET Tracer Development: Assessment in Nonhuman Primates.
Barret O, Zhang L, Alagille D, Constantinescu CC, Sandiego C, Papin C, Sullivan JM, Morley T, Carroll VM, Seibyl J, Chen J, Lee C, Villalobos A, Gray D, McCarthy TJ, Tamagnan G. Barret O, et al. Among authors: constantinescu cc. J Nucl Med. 2021 Sep 1;62(9):1307-1313. doi: 10.2967/jnumed.120.256008. Epub 2021 Feb 12. J Nucl Med. 2021. PMID: 33579806 Free PMC article.
Design, Synthesis, and Evaluation of (2-Aminocyclopropyl)phenyl Derivatives as Novel Positron Emission Tomography Imaging Agents for Lysine-Specific Demethylase 1 in the Brain.
Hattori Y, Matsuda S, Baba R, Matsumiya K, Iwasaki S, Constantinescu CC, Morley TJ, Carroll VM, Papin C, Gouasmat A, Alagille D, Tamagnan G, Koike T. Hattori Y, et al. Among authors: constantinescu cc. J Med Chem. 2021 Apr 8;64(7):3780-3793. doi: 10.1021/acs.jmedchem.0c01937. Epub 2021 Mar 17. J Med Chem. 2021. PMID: 33729758
Design and synthesis of aryl-piperidine derivatives as potent and selective PET tracers for cholesterol 24-hydroxylase (CH24H).
Ikeda S, Kajita Y, Miyamoto M, Matsumiya K, Ishii T, Nishi T, Gay SC, Lane W, Constantinescu CC, Alagille D, Papin C, Tamagnan G, Kuroita T, Koike T. Ikeda S, et al. Among authors: constantinescu cc. Eur J Med Chem. 2022 Oct 5;240:114612. doi: 10.1016/j.ejmech.2022.114612. Epub 2022 Jul 14. Eur J Med Chem. 2022. PMID: 35863274 Free article.
Clinical evaluation of [18F] JNJ-64326067, a novel candidate PET tracer for the detection of tau pathology in Alzheimer's disease.
Schmidt ME, Janssens L, Moechars D, Rombouts FJR, Timmers M, Barret O, Constantinescu CC, Madonia J, Russell DS, Sandiego CM, Kolb H. Schmidt ME, et al. Among authors: constantinescu cc. Eur J Nucl Med Mol Imaging. 2020 Dec;47(13):3176-3185. doi: 10.1007/s00259-020-04880-1. Epub 2020 Jun 13. Eur J Nucl Med Mol Imaging. 2020. PMID: 32535652 Free PMC article.
Evaluation of Dosimetry, Quantitative Methods, and Test-Retest Variability of 18F-PI-2620 PET for the Assessment of Tau Deposits in the Human Brain.
Bullich S, Barret O, Constantinescu C, Sandiego C, Mueller A, Berndt M, Papin C, Perrotin A, Koglin N, Kroth H, Pfeifer A, Tamagnan G, Madonia J, Seibyl JP, Marek K, De Santi S, Dinkelborg LM, Stephens AW. Bullich S, et al. J Nucl Med. 2020 Jun;61(6):920-927. doi: 10.2967/jnumed.119.236240. Epub 2019 Nov 11. J Nucl Med. 2020. PMID: 31712324 Free PMC article.
38 results