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The Dangers of Using Cq to Quantify Nucleic Acid in Biological Samples: A Lesson From COVID-19.
Evans D, Cowen S, Kammel M, O'Sullivan DM, Stewart G, Grunert HP, Moran-Gilad J, Verwilt J, In J, Vandesompele J, Harris K, Hong KH, Storey N, Hingley-Wilson S, Dühring U, Bae YK, Foy CA, Braybrook J, Zeichhardt H, Huggett JF. Evans D, et al. Among authors: harris k. Clin Chem. 2021 Dec 30;68(1):153-162. doi: 10.1093/clinchem/hvab219. Clin Chem. 2021. PMID: 34633030
The use of digital PCR to improve the application of quantitative molecular diagnostic methods for tuberculosis.
Devonshire AS, O'Sullivan DM, Honeyborne I, Jones G, Karczmarczyk M, Pavšič J, Gutteridge A, Milavec M, Mendoza P, Schimmel H, Van Heuverswyn F, Gorton R, Cirillo DM, Borroni E, Harris K, Barnard M, Heydenrych A, Ndusilo N, Wallis CL, Pillay K, Barry T, Reddington K, Richter E, Mozioğlu E, Akyürek S, Yalçınkaya B, Akgoz M, Žel J, Foy CA, McHugh TD, Huggett JF. Devonshire AS, et al. Among authors: harris k. BMC Infect Dis. 2016 Aug 3;16:366. doi: 10.1186/s12879-016-1696-7. BMC Infect Dis. 2016. PMID: 27487852 Free PMC article.
Discordant bioinformatic predictions of antimicrobial resistance from whole-genome sequencing data of bacterial isolates: an inter-laboratory study.
Doyle RM, O'Sullivan DM, Aller SD, Bruchmann S, Clark T, Coello Pelegrin A, Cormican M, Diez Benavente E, Ellington MJ, McGrath E, Motro Y, Phuong Thuy Nguyen T, Phelan J, Shaw LP, Stabler RA, van Belkum A, van Dorp L, Woodford N, Moran-Gilad J, Huggett JF, Harris KA. Doyle RM, et al. Microb Genom. 2020 Feb;6(2):e000335. doi: 10.1099/mgen.0.000335. Epub 2020 Feb 12. Microb Genom. 2020. PMID: 32048983 Free PMC article.
Current and future challenges in quality assurance in molecular diagnostics.
Ahmad-Nejad P, Ashavaid T, Vacaflores Salinas A, Huggett J, Harris K, Linder MW, Baluchova K, Steimer W, Payne DA; IFCC Committee for Molecular Diagnostics (C-MD). Ahmad-Nejad P, et al. Among authors: harris k. Clin Chim Acta. 2021 Aug;519:239-246. doi: 10.1016/j.cca.2021.05.004. Epub 2021 May 8. Clin Chim Acta. 2021. PMID: 33971158
An inter-laboratory study to investigate the impact of the bioinformatics component on microbiome analysis using mock communities.
O'Sullivan DM, Doyle RM, Temisak S, Redshaw N, Whale AS, Logan G, Huang J, Fischer N, Amos GCA, Preston MD, Marchesi JR, Wagner J, Parkhill J, Motro Y, Denise H, Finn RD, Harris KA, Kay GL, O'Grady J, Ransom-Jones E, Wu H, Laing E, Studholme DJ, Benavente ED, Phelan J, Clark TG, Moran-Gilad J, Huggett JF. O'Sullivan DM, et al. Sci Rep. 2021 May 19;11(1):10590. doi: 10.1038/s41598-021-89881-2. Sci Rep. 2021. PMID: 34012005 Free PMC article.
Detection of Mycobacterium tuberculosis complex DNA in CD34-positive peripheral blood mononuclear cells of asymptomatic tuberculosis contacts: an observational study.
Belay M, Tulu B, Younis S, Jolliffe DA, Tayachew D, Manwandu H, Abozen T, Tirfie EA, Tegegn M, Zewude A, Forrest S, Mayito J, Huggett JF, Jones GM, O'Sullivan DM, Martineau HM, Noursadeghi M, Chandran A, Harris KA, Nikolayevskyy V, Demaret J, Berg S, Vordermeier M, Balcha TT, Aseffa A, Ameni G, Abebe M, Reece ST, Martineau AR. Belay M, et al. Lancet Microbe. 2021 Jun;2(6):e267-e275. doi: 10.1016/S2666-5247(21)00043-4. Lancet Microbe. 2021. PMID: 34100007 Free PMC article.
Generation of Novel Severe Acute Respiratory Syndrome Coronavirus 2 Variants on the B.1.1.7 Lineage in 3 Patients With Advanced Human Immunodeficiency Virus-1 Disease.
Riddell AC, Kele B, Harris K, Bible J, Murphy M, Dakshina S, Storey N, Owoyemi D, Pade C, Gibbons JM, Harrington D, Alexander E, McKnight Á, Cutino-Moguel T. Riddell AC, et al. Among authors: harris k. Clin Infect Dis. 2022 Nov 30;75(11):2016-2018. doi: 10.1093/cid/ciac409. Clin Infect Dis. 2022. PMID: 35616095 Free PMC article.
3,426 results