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A multifunctional mouse model to study the role of Samd3.
Peters AE, Knöpper K, Grafen A, Kastenmüller W. Peters AE, et al. Among authors: kastenmuller w. Eur J Immunol. 2022 Feb;52(2):328-337. doi: 10.1002/eji.202149469. Epub 2021 Nov 7. Eur J Immunol. 2022. PMID: 34626120 Free article.
Spatiotemporal regulation of type I interferon expression determines the antiviral polarization of CD4+ T cells.
De Giovanni M, Cutillo V, Giladi A, Sala E, Maganuco CG, Medaglia C, Di Lucia P, Bono E, Cristofani C, Consolo E, Giustini L, Fiore A, Eickhoff S, Kastenmüller W, Amit I, Kuka M, Iannacone M. De Giovanni M, et al. Among authors: kastenmuller w. Nat Immunol. 2020 Mar;21(3):321-330. doi: 10.1038/s41590-020-0596-6. Epub 2020 Feb 17. Nat Immunol. 2020. PMID: 32066949 Free PMC article.
BATF3 programs CD8+ T cell memory.
Ataide MA, Komander K, Knöpper K, Peters AE, Wu H, Eickhoff S, Gogishvili T, Weber J, Grafen A, Kallies A, Garbi N, Einsele H, Hudecek M, Gasteiger G, Hölzel M, Vaeth M, Kastenmüller W. Ataide MA, et al. Among authors: kastenmuller w. Nat Immunol. 2020 Nov;21(11):1397-1407. doi: 10.1038/s41590-020-0786-2. Epub 2020 Sep 28. Nat Immunol. 2020. PMID: 32989328
Neutrophils self-limit swarming to contain bacterial growth in vivo.
Kienle K, Glaser KM, Eickhoff S, Mihlan M, Knöpper K, Reátegui E, Epple MW, Gunzer M, Baumeister R, Tarrant TK, Germain RN, Irimia D, Kastenmüller W, Lämmermann T. Kienle K, et al. Among authors: kastenmuller w. Science. 2021 Jun 18;372(6548):eabe7729. doi: 10.1126/science.abe7729. Science. 2021. PMID: 34140358 Free PMC article.
Effector differentiation downstream of lineage commitment in ILC1s is driven by Hobit across tissues.
Friedrich C, Taggenbrock RLRE, Doucet-Ladevèze R, Golda G, Moenius R, Arampatzi P, Kragten NAM, Kreymborg K, Gomez de Agüero M, Kastenmüller W, Saliba AE, Grün D, van Gisbergen KPJM, Gasteiger G. Friedrich C, et al. Among authors: kastenmuller w. Nat Immunol. 2021 Oct;22(10):1256-1267. doi: 10.1038/s41590-021-01013-0. Epub 2021 Aug 30. Nat Immunol. 2021. PMID: 34462601 Free PMC article.
Type 1 conventional dendritic cells maintain and guide the differentiation of precursors of exhausted T cells in distinct cellular niches.
Dähling S, Mansilla AM, Knöpper K, Grafen A, Utzschneider DT, Ugur M, Whitney PG, Bachem A, Arampatzi P, Imdahl F, Kaisho T, Zehn D, Klauschen F, Garbi N, Kallies A, Saliba AE, Gasteiger G, Bedoui S, Kastenmüller W. Dähling S, et al. Among authors: kastenmuller w. Immunity. 2022 Apr 12;55(4):656-670.e8. doi: 10.1016/j.immuni.2022.03.006. Epub 2022 Apr 1. Immunity. 2022. PMID: 35366396 Free article.
MYB orchestrates T cell exhaustion and response to checkpoint inhibition.
Tsui C, Kretschmer L, Rapelius S, Gabriel SS, Chisanga D, Knöpper K, Utzschneider DT, Nüssing S, Liao Y, Mason T, Torres SV, Wilcox SA, Kanev K, Jarosch S, Leube J, Nutt SL, Zehn D, Parish IA, Kastenmüller W, Shi W, Buchholz VR, Kallies A. Tsui C, et al. Among authors: kastenmuller w. Nature. 2022 Sep;609(7926):354-360. doi: 10.1038/s41586-022-05105-1. Epub 2022 Aug 17. Nature. 2022. PMID: 35978192 Free PMC article.
Lymphatic migration of unconventional T cells promotes site-specific immunity in distinct lymph nodes.
Ataide MA, Knöpper K, Cruz de Casas P, Ugur M, Eickhoff S, Zou M, Shaikh H, Trivedi A, Grafen A, Yang T, Prinz I, Ohlsen K, Gomez de Agüero M, Beilhack A, Huehn J, Gaya M, Saliba AE, Gasteiger G, Kastenmüller W. Ataide MA, et al. Among authors: kastenmuller w. Immunity. 2022 Oct 11;55(10):1813-1828.e9. doi: 10.1016/j.immuni.2022.07.019. Epub 2022 Aug 23. Immunity. 2022. PMID: 36002023 Free article.
Mitochondrial dysfunction promotes the transition of precursor to terminally exhausted T cells through HIF-1α-mediated glycolytic reprogramming.
Wu H, Zhao X, Hochrein SM, Eckstein M, Gubert GF, Knöpper K, Mansilla AM, Öner A, Doucet-Ladevèze R, Schmitz W, Ghesquière B, Theurich S, Dudek J, Gasteiger G, Zernecke A, Kobold S, Kastenmüller W, Vaeth M. Wu H, et al. Among authors: kastenmuller w. Nat Commun. 2023 Oct 27;14(1):6858. doi: 10.1038/s41467-023-42634-3. Nat Commun. 2023. PMID: 37891230 Free PMC article.
71 results