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CD73-mediated adenosine production by CD8 T cell-derived extracellular vesicles constitutes an intrinsic mechanism of immune suppression.
Schneider E, Winzer R, Rissiek A, Ricklefs I, Meyer-Schwesinger C, Ricklefs FL, Bauche A, Behrends J, Reimer R, Brenna S, Wasielewski H, Lauten M, Rissiek B, Puig B, Cortesi F, Magnus T, Fliegert R, Müller CE, Gagliani N, Tolosa E. Schneider E, et al. Among authors: winzer r. Nat Commun. 2021 Oct 8;12(1):5911. doi: 10.1038/s41467-021-26134-w. Nat Commun. 2021. PMID: 34625545 Free PMC article.
2'-Deoxyadenosine 5'-diphosphoribose is an endogenous TRPM2 superagonist.
Fliegert R, Bauche A, Wolf Pérez AM, Watt JM, Rozewitz MD, Winzer R, Janus M, Gu F, Rosche A, Harneit A, Flato M, Moreau C, Kirchberger T, Wolters V, Potter BVL, Guse AH. Fliegert R, et al. Among authors: winzer r. Nat Chem Biol. 2017 Sep;13(9):1036-1044. doi: 10.1038/nchembio.2415. Epub 2017 Jun 26. Nat Chem Biol. 2017. PMID: 28671679 Free PMC article.
Generation and Function of Non-cell-bound CD73 in Inflammation.
Schneider E, Rissiek A, Winzer R, Puig B, Rissiek B, Haag F, Mittrücker HW, Magnus T, Tolosa E. Schneider E, et al. Among authors: winzer r. Front Immunol. 2019 Jul 26;10:1729. doi: 10.3389/fimmu.2019.01729. eCollection 2019. Front Immunol. 2019. PMID: 31404305 Free PMC article. Review.
2-Methoxyestradiol and its derivatives inhibit store-operated Ca2+ entry in T cells: Identification of a new and potent inhibitor.
Löhndorf A, Hosang L, Dohle W, Odoardi F, Waschkowski SA, Rosche A, Bauche A, Winzer R, Tolosa E, Windhorst S, Marry S, Flügel A, Potter BVL, Diercks BP, Guse AH. Löhndorf A, et al. Among authors: winzer r. Biochim Biophys Acta Mol Cell Res. 2021 May;1868(6):118988. doi: 10.1016/j.bbamcr.2021.118988. Epub 2021 Feb 10. Biochim Biophys Acta Mol Cell Res. 2021. PMID: 33581218 Free PMC article.
The role of the ATP-adenosine axis in ischemic stroke.
Schädlich IS, Winzer R, Stabernack J, Tolosa E, Magnus T, Rissiek B. Schädlich IS, et al. Among authors: winzer r. Semin Immunopathol. 2023 May;45(3):347-365. doi: 10.1007/s00281-023-00987-3. Epub 2023 Mar 14. Semin Immunopathol. 2023. PMID: 36917241 Free PMC article. Review.
The Clinical Significance of CD73 in Cancer.
Bach N, Winzer R, Tolosa E, Fiedler W, Brauneck F. Bach N, et al. Among authors: winzer r. Int J Mol Sci. 2023 Jul 21;24(14):11759. doi: 10.3390/ijms241411759. Int J Mol Sci. 2023. PMID: 37511518 Free PMC article. Review.
69 results