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Screening Hit to Clinical Candidate: Discovery of BMS-963272, a Potent, Selective MGAT2 Inhibitor for the Treatment of Metabolic Disorders.
J Med Chem. 2021 Oct 14;64(19):14773-14792. doi: 10.1021/acs.jmedchem.1c01356. Epub 2021 Oct 6.
J Med Chem. 2021.
PMID: 34613725
Discovery of 6-(aminomethyl)-5-(2,4-dichlorophenyl)-7-methylimidazo[1,2-a]pyrimidine-2-carboxamides as potent, selective dipeptidyl peptidase-4 (DPP4) inhibitors.
Meng W, Brigance RP, Chao HJ, Fura A, Harrity T, Marcinkeviciene J, O'Connor SP, Tamura JK, Xie D, Zhang Y, Klei HE, Kish K, Weigelt CA, Turdi H, Wang A, Zahler R, Kirby MS, Hamann LG.
Meng W, et al. Among authors: turdi h.
J Med Chem. 2010 Aug 12;53(15):5620-8. doi: 10.1021/jm100634a.
J Med Chem. 2010.
PMID: 20684603
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Discovery of 2-(phenoxypyridine)-3-phenylureas as small molecule P2Y1 antagonists.
Chao H, Turdi H, Herpin TF, Roberge JY, Liu Y, Schnur DM, Poss MA, Rehfuss R, Hua J, Wu Q, Price LA, Abell LM, Schumacher WA, Bostwick JS, Steinbacher TE, Stewart AB, Ogletree ML, Huang CS, Chang M, Cacace AM, Arcuri MJ, Celani D, Wexler RR, Lawrence RM.
Chao H, et al. Among authors: turdi h.
J Med Chem. 2013 Feb 28;56(4):1704-14. doi: 10.1021/jm301708u. Epub 2013 Feb 18.
J Med Chem. 2013.
PMID: 23368907
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Characterization of monoacylglycerol acyltransferase 2 inhibitors by a novel probe in binding assays.
Ma Z, Chao HJ, Turdi H, Hangeland JJ, Friends T, Kopcho LM, Lawrence RM, Cheng D.
Ma Z, et al. Among authors: turdi h.
Anal Biochem. 2016 May 15;501:48-55. doi: 10.1016/j.ab.2016.02.012. Epub 2016 Feb 27.
Anal Biochem. 2016.
PMID: 26925857
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