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Detecting genome-wide directional effects of transcription factor binding on polygenic disease risk.
Reshef YA, Finucane HK, Kelley DR, Gusev A, Kotliar D, Ulirsch JC, Hormozdiari F, Nasser J, O'Connor L, van de Geijn B, Loh PR, Grossman SR, Bhatia G, Gazal S, Palamara PF, Pinello L, Patterson N, Adams RP, Price AL. Reshef YA, et al. Among authors: kelley dr. Nat Genet. 2018 Oct;50(10):1483-1493. doi: 10.1038/s41588-018-0196-7. Epub 2018 Sep 3. Nat Genet. 2018. PMID: 30177862 Free PMC article.
Cross-species regulatory sequence activity prediction.
Kelley DR. Kelley DR. PLoS Comput Biol. 2020 Jul 20;16(7):e1008050. doi: 10.1371/journal.pcbi.1008050. eCollection 2020 Jul. PLoS Comput Biol. 2020. PMID: 32687525 Free PMC article.
Perspectives on ENCODE.
ENCODE Project Consortium; Snyder MP, Gingeras TR, Moore JE, Weng Z, Gerstein MB, Ren B, Hardison RC, Stamatoyannopoulos JA, Graveley BR, Feingold EA, Pazin MJ, Pagan M, Gilchrist DA, Hitz BC, Cherry JM, Bernstein BE, Mendenhall EM, Zerbino DR, Frankish A, Flicek P, Myers RM. ENCODE Project Consortium, et al. Nature. 2020 Jul;583(7818):693-698. doi: 10.1038/s41586-020-2449-8. Epub 2020 Jul 29. Nature. 2020. PMID: 32728248 Free PMC article.
Predicting 3D genome folding from DNA sequence with Akita.
Fudenberg G, Kelley DR, Pollard KS. Fudenberg G, et al. Among authors: kelley dr. Nat Methods. 2020 Nov;17(11):1111-1117. doi: 10.1038/s41592-020-0958-x. Epub 2020 Oct 12. Nat Methods. 2020. PMID: 33046897 Free PMC article.
72 results