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Fragment-based lead discovery of indazole-based compounds as AXL kinase inhibitors.
Ng PS, Foo K, Sim S, Wang G, Huang C, Tan LH, Poulsen A, Liu B, Tee DHY, Ahmad NHB, Wang S, Ke Z, Lee MA, Kwek ZP, Joy J, Anantharajan J, Baburajendran N, Pendharkar V, Manoharan V, Vuddagiri S, Sangthongpitag K, Hill J, Keller TH, Hung AW. Ng PS, et al. Bioorg Med Chem. 2021 Nov 1;49:116437. doi: 10.1016/j.bmc.2021.116437. Epub 2021 Sep 25. Bioorg Med Chem. 2021. PMID: 34600239
Discovery of a Novel Mycobacterial F-ATP Synthase Inhibitor and its Potency in Combination with Diarylquinolines.
Hotra A, Ragunathan P, Ng PS, Seankongsuk P, Harikishore A, Sarathy JP, Saw WG, Lakshmanan U, Sae-Lao P, Kalia NP, Shin J, Kalyanasundaram R, Anbarasu S, Parthasarathy K, Pradeep CN, Makhija H, Dröge P, Poulsen A, Tan JHL, Pethe K, Dick T, Bates RW, Grüber G. Hotra A, et al. Among authors: ng ps. Angew Chem Int Ed Engl. 2020 Aug 3;59(32):13295-13304. doi: 10.1002/anie.202002546. Epub 2020 May 26. Angew Chem Int Ed Engl. 2020. PMID: 32337801
Direct inhibitors of InhA are active against Mycobacterium tuberculosis.
Manjunatha UH, S Rao SP, Kondreddi RR, Noble CG, Camacho LR, Tan BH, Ng SH, Ng PS, Ma NL, Lakshminarayana SB, Herve M, Barnes SW, Yu W, Kuhen K, Blasco F, Beer D, Walker JR, Tonge PJ, Glynne R, Smith PW, Diagana TT. Manjunatha UH, et al. Among authors: ng sh, ng ps. Sci Transl Med. 2015 Jan 7;7(269):269ra3. doi: 10.1126/scitranslmed.3010597. Sci Transl Med. 2015. PMID: 25568071 Free PMC article.
Effects of Auditory Training in Older Adults.
Lai CY, Ng PS, Chan AHD, Wong FCK. Lai CY, et al. Among authors: ng ps. J Speech Lang Hear Res. 2023 Oct 4;66(10):4137-4149. doi: 10.1044/2023_JSLHR-22-00621. Epub 2023 Sep 1. J Speech Lang Hear Res. 2023. PMID: 37656601
Cyanotriazoles are selective topoisomerase II poisons that rapidly cure trypanosome infections.
Rao SPS, Gould MK, Noeske J, Saldivia M, Jumani RS, Ng PS, René O, Chen YL, Kaiser M, Ritchie R, Francisco AF, Johnson N, Patra D, Cheung H, Deniston C, Schenk AD, Cortopassi WA, Schmidt RS, Wiedemar N, Thomas B, Palkar R, Ghafar NA, Manoharan V, Luu C, Gable JE, Wan KF, Myburgh E, Mottram JC, Barnes W, Walker J, Wartchow C, Aziz N, Osborne C, Wagner J, Sarko C, Kelly JM, Manjunatha UH, Mäser P, Jiricek J, Lakshminarayana SB, Barrett MP, Diagana TT. Rao SPS, et al. Among authors: ng ps. Science. 2023 Jun 30;380(6652):1349-1356. doi: 10.1126/science.adh0614. Epub 2023 Jun 29. Science. 2023. PMID: 37384702 Free article.
ALS Treatment- We Still Await the "Magic Cocktail".
Koh JS, Fam SR, Ng PS, Umapathi T. Koh JS, et al. Among authors: ng ps. Ann Indian Acad Neurol. 2022 Jul-Aug;25(4):577-578. doi: 10.4103/aian.aian_397_22. Epub 2022 Aug 4. Ann Indian Acad Neurol. 2022. PMID: 36211158 Free PMC article. No abstract available.
89 results