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Progressive Motor Neuron Pathology and the Role of Astrocytes in a Human Stem Cell Model of VCP-Related ALS.
Hall CE, Yao Z, Choi M, Tyzack GE, Serio A, Luisier R, Harley J, Preza E, Arber C, Crisp SJ, Watson PMD, Kullmann DM, Abramov AY, Wray S, Burley R, Loh SHY, Martins LM, Stevens MM, Luscombe NM, Sibley CR, Lakatos A, Ule J, Gandhi S, Patani R. Hall CE, et al. Among authors: luisier r. Cell Rep. 2017 May 30;19(9):1739-1749. doi: 10.1016/j.celrep.2017.05.024. Cell Rep. 2017. PMID: 28564594 Free PMC article.
Intron retention and nuclear loss of SFPQ are molecular hallmarks of ALS.
Luisier R, Tyzack GE, Hall CE, Mitchell JS, Devine H, Taha DM, Malik B, Meyer I, Greensmith L, Newcombe J, Ule J, Luscombe NM, Patani R. Luisier R, et al. Nat Commun. 2018 May 22;9(1):2010. doi: 10.1038/s41467-018-04373-8. Nat Commun. 2018. PMID: 29789581 Free PMC article.
Cytoplasmic cleavage of IMPA1 3' UTR is necessary for maintaining axon integrity.
Andreassi C, Luisier R, Crerar H, Darsinou M, Blokzijl-Franke S, Lenn T, Luscombe NM, Cuda G, Gaspari M, Saiardi A, Riccio A. Andreassi C, et al. Among authors: luisier r. Cell Rep. 2021 Feb 23;34(8):108778. doi: 10.1016/j.celrep.2021.108778. Cell Rep. 2021. PMID: 33626357 Free PMC article.
20 results