Zwinderman MRH - Search Results

1

Deposition Bias of Chromatin Proteins Inverts under DNA Replication Stress Conditions.

Zwinderman MRH, Lobo TJ, van der Wouden PE, Spierings DCJ, van Vugt MATM, Lansdorp PM, Guryev V, Dekker FJ. Zwinderman MRH, et al. ACS Chem Biol. 2021 Nov 19;16(11):2193-2201. doi: 10.1021/acschembio.1c00321. Epub 2021 Sep 30. ACS Chem Biol. 2021. PMID: 34592816 Free PMC article.

2

Histone deacetylase 3 (HDAC 3) as emerging drug target in NF-κB-mediated inflammation.

Leus NG, Zwinderman MR, Dekker FJ. Leus NG, et al. Curr Opin Chem Biol. 2016 Aug;33:160-8. doi: 10.1016/j.cbpa.2016.06.019. Epub 2016 Jun 29. Curr Opin Chem Biol. 2016. PMID: 27371876 Free PMC article. Review.

3

Activity-Based Probes for 15-Lipoxygenase-1.

Eleftheriadis N, Thee SA, Zwinderman MR, Leus NG, Dekker FJ. Eleftheriadis N, et al. Angew Chem Int Ed Engl. 2016 Sep 26;55(40):12300-5. doi: 10.1002/anie.201606876. Epub 2016 Sep 9. Angew Chem Int Ed Engl. 2016. PMID: 27612308 Free PMC article.

4

Design, Multicomponent Synthesis, and Anticancer Activity of a Focused Histone Deacetylase (HDAC) Inhibitor Library with Peptoid-Based Cap Groups.

Krieger V, Hamacher A, Gertzen CGW, Senger J, Zwinderman MRH, Marek M, Romier C, Dekker FJ, Kurz T, Jung M, Gohlke H, Kassack MU, Hansen FK. Krieger V, et al. Among authors: zwinderman mrh. J Med Chem. 2017 Jul 13;60(13):5493-5506. doi: 10.1021/acs.jmedchem.7b00197. Epub 2017 Jun 16. J Med Chem. 2017. PMID: 28574690

5

The Process and Strategy for Developing Selective Histone Deacetylase 3 Inhibitors.

Cao F, Zwinderman MRH, Dekker FJ. Cao F, et al. Among authors: zwinderman mrh. Molecules. 2018 Mar 2;23(3):551. doi: 10.3390/molecules23030551. Molecules. 2018. PMID: 29498635 Free PMC article. Review.

6

Identification of potential antivirulence agents by substitution-oriented screening for inhibitors of Streptococcus pyogenes sortase A.

Wójcik M, Eleftheriadis N, Zwinderman MRH, Dömling ASS, Dekker FJ, Boersma YL. Wójcik M, et al. Among authors: zwinderman mrh. Eur J Med Chem. 2019 Jan 1;161:93-100. doi: 10.1016/j.ejmech.2018.10.027. Epub 2018 Oct 15. Eur J Med Chem. 2019. PMID: 30343193

7

Inhibitory selectivity among class I HDACs has a major impact on inflammatory gene expression in macrophages.

Cao F, Zwinderman MRH, van Merkerk R, Ettema PE, Quax WJ, Dekker FJ. Cao F, et al. Among authors: zwinderman mrh. Eur J Med Chem. 2019 Sep 1;177:457-466. doi: 10.1016/j.ejmech.2019.05.038. Epub 2019 May 18. Eur J Med Chem. 2019. PMID: 31181405

8

Inhibition of histone deacetylase 1 (HDAC1) and HDAC2 enhances CRISPR/Cas9 genome editing.

Liu B, Chen S, Rose A, Chen D, Cao F, Zwinderman M, Kiemel D, Aïssi M, Dekker FJ, Haisma HJ. Liu B, et al. Nucleic Acids Res. 2020 Jan 24;48(2):517-532. doi: 10.1093/nar/gkz1136. Nucleic Acids Res. 2020. PMID: 31799598 Free PMC article.

9

Induced protein degradation of histone deacetylases 3 (HDAC3) by proteolysis targeting chimera (PROTAC).

Cao F, de Weerd S, Chen D, Zwinderman MRH, van der Wouden PE, Dekker FJ. Cao F, et al. Among authors: zwinderman mrh. Eur J Med Chem. 2020 Dec 15;208:112800. doi: 10.1016/j.ejmech.2020.112800. Epub 2020 Sep 6. Eur J Med Chem. 2020. PMID: 32971411 Free article.

10

Targeting HDAC Complexes in Asthma and COPD.

Zwinderman MRH, de Weerd S, Dekker FJ. Zwinderman MRH, et al. Epigenomes. 2019 Sep 7;3(3):19. doi: 10.3390/epigenomes3030019. Epigenomes. 2019. PMID: 34968229 Free PMC article. Review.

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