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Development of a fluorogenic ADAMTS-7 substrate.
Santamaria S, Buemi F, Nuti E, Cuffaro D, De Vita E, Tuccinardi T, Rossello A, Howell S, Mehmood S, Snijders AP, de Groot R. Santamaria S, et al. Among authors: snijders ap. J Enzyme Inhib Med Chem. 2021 Dec;36(1):2160-2169. doi: 10.1080/14756366.2021.1983808. J Enzyme Inhib Med Chem. 2021. PMID: 34587841 Free PMC article.
Circadian rhythms in the absence of the clock gene Bmal1.
Ray S, Valekunja UK, Stangherlin A, Howell SA, Snijders AP, Damodaran G, Reddy AB. Ray S, et al. Among authors: snijders ap. Science. 2020 Feb 14;367(6479):800-806. doi: 10.1126/science.aaw7365. Science. 2020. PMID: 32054765
A small molecule inhibitor of HER3: a proof-of-concept study.
Colomba A, Fitzek M, George R, Weitsman G, Roberts S, Zanetti-Domingues L, Hirsch M, Rolfe DJ, Mehmood S, Madin A, Claus J, Kjaer S, Snijders AP, Ng T, Martin-Fernandez M, Smith DM, Parker PJ. Colomba A, et al. Among authors: snijders ap. Biochem J. 2020 Sep 18;477(17):3329-3347. doi: 10.1042/BCJ20200496. Biochem J. 2020. PMID: 32815546 Free PMC article.
Design of a Potent, Selective, and Brain-Penetrant Inhibitor of Wnt-Deactivating Enzyme Notum by Optimization of a Crystallographic Fragment Hit.
Willis NJ, Mahy W, Sipthorp J, Zhao Y, Woodward HL, Atkinson BN, Bayle ED, Svensson F, Frew S, Jeganathan F, Monaghan A, Benvegnù S, Jolly S, Vecchia L, Ruza RR, Kjær S, Howell S, Snijders AP, Bictash M, Salinas PC, Vincent JP, Jones EY, Whiting P, Fish PV. Willis NJ, et al. Among authors: snijders ap. J Med Chem. 2022 May 26;65(10):7212-7230. doi: 10.1021/acs.jmedchem.2c00162. Epub 2022 May 10. J Med Chem. 2022. PMID: 35536179 Free PMC article.
167 results