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The E3 ubiquitin ligase TRIM31 plays a critical role in hypertensive nephropathy by promoting proteasomal degradation of MAP3K7 in the TGF-β1 signaling pathway.
Zhang J, Cao L, Wang X, Li Q, Zhang M, Cheng C, Yu L, Xue F, Sui W, Sun S, Li N, Bu P, Liu B, Gao F, Zhen J, Su G, Zhang C, Gao C, Zhang M, Zhang Y. Zhang J, et al. Among authors: cao l. Cell Death Differ. 2022 Mar;29(3):556-567. doi: 10.1038/s41418-021-00874-0. Epub 2021 Sep 28. Cell Death Differ. 2022. PMID: 34584221 Free PMC article.
A LATS2 and ALKBH5 positive feedback loop supports their oncogenic roles.
Cao L, Han R, Zhao Y, Qin X, Li Q, Xiong H, Kong Y, Liu Z, Li Z, Dong F, Li T, Zhao X, Lei L, Zhao Q, Liu D, Wang B, Wu X. Cao L, et al. Cell Rep. 2024 Apr 23;43(4):114032. doi: 10.1016/j.celrep.2024.114032. Epub 2024 Apr 2. Cell Rep. 2024. PMID: 38568805 Free article.
The Functions and Mechanisms of PR-DUB in Malignancy.
Cao L, Li R, Wu X. Cao L, et al. Front Mol Biosci. 2021 Mar 12;8:657150. doi: 10.3389/fmolb.2021.657150. eCollection 2021. Front Mol Biosci. 2021. PMID: 33796551 Free PMC article. Review.
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