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Discovery of 5-{4-[(7-Ethyl-6-oxo-5,6-dihydro-1,5-naphthyridin-3-yl)methyl]piperazin-1-yl}-N-methylpyridine-2-carboxamide (AZD5305): A PARP1-DNA Trapper with High Selectivity for PARP1 over PARP2 and Other PARPs.
Johannes JW, Balazs A, Barratt D, Bista M, Chuba MD, Cosulich S, Critchlow SE, Degorce SL, Di Fruscia P, Edmondson SD, Embrey K, Fawell S, Ghosh A, Gill SJ, Gunnarsson A, Hande SM, Heightman TD, Hemsley P, Illuzzi G, Lane J, Larner C, Leo E, Liu L, Madin A, Martin S, McWilliams L, O'Connor MJ, Orme JP, Pachl F, Packer MJ, Pei X, Pike A, Schimpl M, She H, Staniszewska AD, Talbot V, Underwood E, Varnes JG, Xue L, Yao T, Zhang K, Zhang AX, Zheng X. Johannes JW, et al. Among authors: liu l. J Med Chem. 2021 Oct 14;64(19):14498-14512. doi: 10.1021/acs.jmedchem.1c01012. Epub 2021 Sep 27. J Med Chem. 2021. PMID: 34570508
Elucidating the Onset of Cross-Protective Immunity after Intranasal Vaccination with the Attenuated African Swine Fever Vaccine Candidate BA71ΔCD2.
Marín-Moraleda D, Muñoz-Basagoiti J, Tort-Miró A, Navas MJ, Muñoz M, Vidal E, Cobos À, Martín-Mur B, Meas S, Motuzova V, Chang CY, Gut M, Accensi F, Pina-Pedrero S, Núñez JI, Esteve-Codina A, Gavrilov B, Rodriguez F, Liu L, Argilaguet J. Marín-Moraleda D, et al. Among authors: liu l. Vaccines (Basel). 2024 May 9;12(5):517. doi: 10.3390/vaccines12050517. Vaccines (Basel). 2024. PMID: 38793768
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