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Discovery of Novel UDP-N-Acetylglucosamine Acyltransferase (LpxA) Inhibitors with Activity against Pseudomonas aeruginosa.
J Med Chem. 2021 Oct 14;64(19):14377-14425. doi: 10.1021/acs.jmedchem.1c00888. Epub 2021 Sep 27.
J Med Chem. 2021.
PMID: 34569791
Antibacterial medicinal chemistry - what can we design for?
Parkes AL.
Parkes AL.
Expert Opin Drug Discov. 2020 Sep;15(9):1005-1013. doi: 10.1080/17460441.2020.1767065. Epub 2020 May 26.
Expert Opin Drug Discov. 2020.
PMID: 32452235
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Hybrid antibiotics - clinical progress and novel designs.
Parkes AL, Yule IA.
Parkes AL, et al.
Expert Opin Drug Discov. 2016 Jul;11(7):665-80. doi: 10.1080/17460441.2016.1187597. Epub 2016 May 31.
Expert Opin Drug Discov. 2016.
PMID: 27169483
Review.
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Asymmetric conjugate reductions with samarium diiodide: asymmetric synthesis of (2S,3R)- and (2S,3S)-[2-2H,3-2H]-leucine-(S)-phenylalanine dipeptides and (2S,3R)-[2-(2)H,3-2H]-phenylalanine methyl ester.
Davies SG, Rodriguez-Solla H, Tamayo JA, Cowley AR, Concellon C, Garner AC, Parkes AL, Smith AD.
Davies SG, et al. Among authors: parkes al.
Org Biomol Chem. 2005 Apr 21;3(8):1435-47. doi: 10.1039/b500566c. Epub 2005 Mar 17.
Org Biomol Chem. 2005.
PMID: 15827639
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RNA: prebiotic product, or biotic invention?
Anastasi C, Buchet FF, Crowe MA, Parkes AL, Powner MW, Smith JM, Sutherland JD.
Anastasi C, et al. Among authors: parkes al.
Chem Biodivers. 2007 Apr;4(4):721-39. doi: 10.1002/cbdv.200790060.
Chem Biodivers. 2007.
PMID: 17443885
Review.
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On the prebiotic synthesis of ribonucleotides: photoanomerisation of cytosine nucleosides and nucleotides revisited.
Powner MW, Anastasi C, Crowe MA, Parkes AL, Raftery J, Sutherland JD.
Powner MW, et al. Among authors: parkes al.
Chembiochem. 2007 Jul 9;8(10):1170-9. doi: 10.1002/cbic.200700098.
Chembiochem. 2007.
PMID: 17549787
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Expeditious, potentially primordial, aminoacylation of nucleotides.
Biron JP, Parkes AL, Pascal R, Sutherland JD.
Biron JP, et al. Among authors: parkes al.
Angew Chem Int Ed Engl. 2005 Oct 21;44(41):6731-4. doi: 10.1002/anie.200501591.
Angew Chem Int Ed Engl. 2005.
PMID: 16187390
No abstract available.
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