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CD147 antibody specifically and effectively inhibits infection and cytokine storm of SARS-CoV-2 and its variants delta, alpha, beta, and gamma.
Geng J, Chen L, Yuan Y, Wang K, Wang Y, Qin C, Wu G, Chen R, Zhang Z, Wei D, Du P, Zhang J, Lin P, Zhang K, Deng Y, Xu K, Liu J, Sun X, Guo T, Yang X, Wu J, Jiang J, Li L, Zhang K, Wang Z, Zhang J, Yan Q, Zhu H, Zheng Z, Miao J, Fu X, Yang F, Chen X, Tang H, Zhang Y, Shi Y, Zhu Y, Pei Z, Huo F, Liang X, Wang Y, Wang Q, Xie W, Li Y, Shi M, Bian H, Zhu P, Chen ZN. Geng J, et al. Among authors: wu g, wu j. Signal Transduct Target Ther. 2021 Sep 25;6(1):347. doi: 10.1038/s41392-021-00760-8. Signal Transduct Target Ther. 2021. PMID: 34564690 Free PMC article.
Age-related rhesus macaque models of COVID-19.
Yu P, Qi F, Xu Y, Li F, Liu P, Liu J, Bao L, Deng W, Gao H, Xiang Z, Xiao C, Lv Q, Gong S, Liu J, Song Z, Qu Y, Xue J, Wei Q, Liu M, Wang G, Wang S, Yu H, Liu X, Huang B, Wang W, Zhao L, Wang H, Ye F, Zhou W, Zhen W, Han J, Wu G, Jin Q, Wang J, Tan W, Qin C. Yu P, et al. Among authors: wu g. Animal Model Exp Med. 2020 Mar 30;3(1):93-97. doi: 10.1002/ame2.12108. eCollection 2020 Mar. Animal Model Exp Med. 2020. PMID: 32318665 Free PMC article.
The pathogenicity of SARS-CoV-2 in hACE2 transgenic mice.
Bao L, Deng W, Huang B, Gao H, Liu J, Ren L, Wei Q, Yu P, Xu Y, Qi F, Qu Y, Li F, Lv Q, Wang W, Xue J, Gong S, Liu M, Wang G, Wang S, Song Z, Zhao L, Liu P, Zhao L, Ye F, Wang H, Zhou W, Zhu N, Zhen W, Yu H, Zhang X, Guo L, Chen L, Wang C, Wang Y, Wang X, Xiao Y, Sun Q, Liu H, Zhu F, Ma C, Yan L, Yang M, Han J, Xu W, Tan W, Peng X, Jin Q, Wu G, Qin C. Bao L, et al. Among authors: wu g. Nature. 2020 Jul;583(7818):830-833. doi: 10.1038/s41586-020-2312-y. Epub 2020 May 7. Nature. 2020. PMID: 32380511
A human neutralizing antibody targets the receptor-binding site of SARS-CoV-2.
Shi R, Shan C, Duan X, Chen Z, Liu P, Song J, Song T, Bi X, Han C, Wu L, Gao G, Hu X, Zhang Y, Tong Z, Huang W, Liu WJ, Wu G, Zhang B, Wang L, Qi J, Feng H, Wang FS, Wang Q, Gao GF, Yuan Z, Yan J. Shi R, et al. Among authors: wu g, wu l. Nature. 2020 Aug;584(7819):120-124. doi: 10.1038/s41586-020-2381-y. Epub 2020 May 26. Nature. 2020. PMID: 32454512
Development of an Inactivated Vaccine Candidate, BBIBP-CorV, with Potent Protection against SARS-CoV-2.
Wang H, Zhang Y, Huang B, Deng W, Quan Y, Wang W, Xu W, Zhao Y, Li N, Zhang J, Liang H, Bao L, Xu Y, Ding L, Zhou W, Gao H, Liu J, Niu P, Zhao L, Zhen W, Fu H, Yu S, Zhang Z, Xu G, Li C, Lou Z, Xu M, Qin C, Wu G, Gao GF, Tan W, Yang X. Wang H, et al. Among authors: wu g. Cell. 2020 Aug 6;182(3):713-721.e9. doi: 10.1016/j.cell.2020.06.008. Epub 2020 Jun 6. Cell. 2020. PMID: 32778225 Free PMC article.
The Infection and Pathogenicity of SARS-CoV-2 Variant B.1.351 in hACE2 Mice.
Chen Q, Huang XY, Tian Y, Fan C, Sun M, Zhou C, Li R, Zhang RR, Wu G, Qin CF. Chen Q, et al. Among authors: wu g. Virol Sin. 2021 Oct;36(5):1232-1235. doi: 10.1007/s12250-021-00452-1. Epub 2021 Sep 27. Virol Sin. 2021. PMID: 34569016 Free PMC article. No abstract available.
One-Year Sustained Cellular and Humoral Immunities in Coronavirus Disease 2019 (COVID-19) Convalescents.
Zhang J, Lin H, Ye B, Zhao M, Zhan J, Dong S, Guo Y, Zhao Y, Li M, Liu S, Zhang H, Xiao W, Guo Y, Yue C, Zhang D, Yang M, Zhang J, Quan C, Shi W, Liu X, Liu P, Jiang Y, Wu G, Gao GF, Liu WJ. Zhang J, et al. Among authors: wu g. Clin Infect Dis. 2022 Aug 24;75(1):e1072-e1081. doi: 10.1093/cid/ciab884. Clin Infect Dis. 2022. PMID: 34609506 Free PMC article.
Design of a mutation-integrated trimeric RBD with broad protection against SARS-CoV-2.
Liang Y, Zhang J, Yuan RY, Wang MY, He P, Su JG, Han ZB, Jin YQ, Hou JW, Zhang H, Zhang XF, Shao S, Hou YN, Liu ZM, Du LF, Shen FJ, Zhou WM, Xu K, Gao RQ, Tang F, Lei ZH, Liu S, Zhen W, Wu JJ, Zheng X, Liu N, Chen S, Ma ZJ, Zheng F, Ren SY, Hu ZY, Huang WJ, Wu GZ, Ke CW, Li QM. Liang Y, et al. Cell Discov. 2022 Feb 15;8(1):17. doi: 10.1038/s41421-022-00383-5. Cell Discov. 2022. PMID: 35169113 Free PMC article.
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