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Discovery of 3,4-dichloro-N-(1H-indol-5-yl)benzamide: A highly potent, selective, and competitive hMAO-B inhibitor with high BBB permeability profile and neuroprotective action.
Bioorg Chem. 2021 Nov;116:105352. doi: 10.1016/j.bioorg.2021.105352. Epub 2021 Sep 11.
Bioorg Chem. 2021.
PMID: 34562673
Optimization study towards more potent thiazolidine-2,4-dione IKK-β modulator: Synthesis, biological evaluation and in silico docking simulation.
Elkamhawy A, Youn Kim N, Hassan AHE, Park JE, Yang JE, Elsherbeny MH, Paik S, Oh KS, Lee BH, Lee MY, Shin KJ, Pae AN, Lee KT, Roh EJ.
Elkamhawy A, et al. Among authors: elsherbeny mh.
Bioorg Chem. 2019 Nov;92:103261. doi: 10.1016/j.bioorg.2019.103261. Epub 2019 Sep 7.
Bioorg Chem. 2019.
PMID: 31542718
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Scaffold Repurposing of In-House Small Molecule Candidates Leads to Discovery of First-in-Class CDK-1/HER-2 Dual Inhibitors: In Vitro and In Silico Screening.
Elkamhawy A, Ammar UM, Paik S, Abdellattif MH, Elsherbeny MH, Lee K, Roh EJ.
Elkamhawy A, et al. Among authors: elsherbeny mh.
Molecules. 2021 Sep 1;26(17):5324. doi: 10.3390/molecules26175324.
Molecules. 2021.
PMID: 34500757
Free PMC article.
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Development of New Meridianin/Leucettine-Derived Hybrid Small Molecules as Nanomolar Multi-Kinase Inhibitors with Antitumor Activity.
Elsherbeny MH, Elkamhawy A, Nada H, Abdellattif MH, Lee K, Roh EJ.
Elsherbeny MH, et al.
Biomedicines. 2021 Sep 1;9(9):1131. doi: 10.3390/biomedicines9091131.
Biomedicines. 2021.
PMID: 34572319
Free PMC article.
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Highly Potent, Selective, and Competitive Indole-Based MAO-B Inhibitors Protect PC12 Cells against 6-Hydroxydopamine- and Rotenone-Induced Oxidative Stress.
Elsherbeny MH, Kim J, Gouda NA, Gotina L, Cho J, Pae AN, Lee K, Park KD, Elkamhawy A, Roh EJ.
Elsherbeny MH, et al.
Antioxidants (Basel). 2021 Oct 19;10(10):1641. doi: 10.3390/antiox10101641.
Antioxidants (Basel). 2021.
PMID: 34679775
Free PMC article.
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2-(3-Bromophenyl)-8-fluoroquinazoline-4-carboxylic Acid as a Novel and Selective Aurora A Kinase Inhibitory Lead with Apoptosis Properties: Design, Synthesis, In Vitro and In Silico Biological Evaluation.
Elsherbeny MH, Ammar UM, Abdellattif MH, Abourehab MAS, Abdeen A, Ibrahim SF, Abdelrahaman D, Mady W, Roh EJ, Elkamhawy A.
Elsherbeny MH, et al.
Life (Basel). 2022 Jun 10;12(6):876. doi: 10.3390/life12060876.
Life (Basel). 2022.
PMID: 35743907
Free PMC article.
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Correction: Elsherbeny et al. 2-(3-Bromophenyl)-8-fluoroquinazoline-4-carboxylic Acid as a Novel and Selective Aurora A Kinase Inhibitory Lead with Apoptosis Properties: Design, Synthesis, In Vitro and In Silico Biological Evaluation. Life 2022, 12, 876.
Elsherbeny MH, Ammar UM, Abdellattif MH, Abourehab MAS, Abdeen A, Ibrahim SF, Abdelrahaman D, Mady W, Roh EJ, Elkamhawy A.
Elsherbeny MH, et al.
Life (Basel). 2024 Mar 22;14(4):423. doi: 10.3390/life14040423.
Life (Basel). 2024.
PMID: 38672808
Free PMC article.
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