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The cAMP response element modulator (CREM) regulates TH2 mediated inflammation.
Verjans E, Ohl K, Reiss LK, van Wijk F, Toncheva AA, Wiener A, Yu Y, Rieg AD, Gaertner VD, Roth J, Knol E, Kabesch M, Wagner N, Uhlig S, Martin C, Tenbrock K. Verjans E, et al. Among authors: van wijk f. Oncotarget. 2015 Nov 17;6(36):38538-51. doi: 10.18632/oncotarget.6041. Oncotarget. 2015. PMID: 26459392 Free PMC article.
Goblet cell scarcity and conjunctival inflammation during treatment with dupilumab in patients with atopic dermatitis.
Bakker DS, Ariens LFM, van Luijk C, van der Schaft J, Thijs JL, Schuttelaar MLA, van Wijk F, Knol EF, Balak DMW, van Dijk MR, de Bruin-Weller MS. Bakker DS, et al. Among authors: van der schaft j, van luijk c, van wijk f, van dijk mr. Br J Dermatol. 2019 May;180(5):1248-1249. doi: 10.1111/bjd.17538. Epub 2019 Feb 4. Br J Dermatol. 2019. PMID: 30597515 Free PMC article. No abstract available.
Dupilumab is very effective in a large cohort of difficult-to-treat adult atopic dermatitis patients: First clinical and biomarker results from the BioDay registry.
Ariëns LFM, van der Schaft J, Bakker DS, Balak D, Romeijn MLE, Kouwenhoven T, Kamsteeg M, Giovannone B, Drylewicz J, van Amerongen CCA, Delemarre EM, Knol EF, van Wijk F, Nierkens S, Thijs JL, Schuttelaar MLA, de Bruin-Weller MS. Ariëns LFM, et al. Among authors: van der schaft j, van amerongen cca, van wijk f. Allergy. 2020 Jan;75(1):116-126. doi: 10.1111/all.14080. Epub 2019 Oct 31. Allergy. 2020. PMID: 31593343
Confirmation of multiple endotypes in atopic dermatitis based on serum biomarkers.
Bakker DS, Nierkens S, Knol EF, Giovannone B, Delemarre EM, van der Schaft J, van Wijk F, de Bruin-Weller MS, Drylewicz J, Thijs JL. Bakker DS, et al. Among authors: van der schaft j, van wijk f. J Allergy Clin Immunol. 2021 Jan;147(1):189-198. doi: 10.1016/j.jaci.2020.04.062. Epub 2020 Jun 8. J Allergy Clin Immunol. 2021. PMID: 32526312 Free article.
Conjunctival inflammation in dupilumab-treated atopic dermatitis comprises a multicellular infiltrate with elevated T1/T17 cytokines: A case series study.
Bakker DS, Ter Linde JJM, Amini MM, Ariëns LFM, van Luijk CM, de Bruin-Weller MS, Thijs JL, Vercoulen Y, van Wijk F. Bakker DS, et al. Among authors: van luijk cm, van wijk f. Allergy. 2021 Dec;76(12):3814-3817. doi: 10.1111/all.15064. Epub 2021 Sep 4. Allergy. 2021. PMID: 34449906 Free PMC article. No abstract available.
149 results