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Selectivity of Lewy body protein interactions along the aggregation pathway of α-synuclein.
Commun Biol. 2021 Sep 23;4(1):1124. doi: 10.1038/s42003-021-02624-x.
Commun Biol. 2021.
PMID: 34556785
Free PMC article.
Unveiling a Selective Mechanism for the Inhibition of α-Synuclein Aggregation by β-Synuclein.
Leitao A, Bhumkar A, Hunter DJB, Gambin Y, Sierecki E.
Leitao A, et al.
Int J Mol Sci. 2018 Jan 24;19(2):334. doi: 10.3390/ijms19020334.
Int J Mol Sci. 2018.
PMID: 29364143
Free PMC article.
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Overexpression of alpha synuclein disrupts APP and Endolysosomal axonal trafficking in a mouse model of synucleinopathy.
Lin S, Leitão ADG, Fang S, Gu Y, Barber S, Gilliard-Telefoni R, Castro A, Sung K, Shen R, Florio JB, Mante ML, Ding J, Spencer B, Masliah E, Rissman RA, Wu C.
Lin S, et al. Among authors: leitao adg.
Neurobiol Dis. 2023 Mar;178:106010. doi: 10.1016/j.nbd.2023.106010. Epub 2023 Jan 23.
Neurobiol Dis. 2023.
PMID: 36702318
Free PMC article.
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Hippocampal Reduction of α-Synuclein via RNA Interference Improves Neuropathology in Alzheimer's Disease Mice.
Leitão ADG, Spencer B, Sarsoza F, Ngolab J, Amalraj J, Masliah E, Wu C, Rissman RA.
Leitão ADG, et al.
J Alzheimers Dis. 2023;95(1):349-361. doi: 10.3233/JAD-230232.
J Alzheimers Dis. 2023.
PMID: 37522208
Free PMC article.
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Novel systemic delivery of a peptide-conjugated antisense oligonucleotide to reduce α-synuclein in a mouse model of Alzheimer's disease.
Leitão ADG, Ahammad RU, Spencer B, Wu C, Masliah E, Rissman RA.
Leitão ADG, et al.
Neurobiol Dis. 2023 Oct 1;186:106285. doi: 10.1016/j.nbd.2023.106285. Epub 2023 Sep 9.
Neurobiol Dis. 2023.
PMID: 37690676
Free article.
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Endosomal sorting drives the formation of axonal prion protein endoggresomes.
Chassefeyre R, Chaiamarit T, Verhelle A, Novak SW, Andrade LR, Leitão ADG, Manor U, Encalada SE.
Chassefeyre R, et al. Among authors: leitao adg.
Sci Adv. 2021 Dec 24;7(52):eabg3693. doi: 10.1126/sciadv.abg3693. Epub 2021 Dec 22.
Sci Adv. 2021.
PMID: 34936461
Free PMC article.
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