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Adipocytes disrupt the translational programme of acute lymphoblastic leukaemia to favour tumour survival and persistence.
Heydt Q, Xintaropoulou C, Clear A, Austin M, Pislariu I, Miraki-Moud F, Cutillas P, Korfi K, Calaminici M, Cawthorn W, Suchacki K, Nagano A, Gribben JG, Smith M, Cavenagh JD, Oakervee H, Castleton A, Taussig D, Peck B, Wilczynska A, McNaughton L, Bonnet D, Mardakheh F, Patel B. Heydt Q, et al. Among authors: mardakheh f. Nat Commun. 2021 Sep 17;12(1):5507. doi: 10.1038/s41467-021-25540-4. Nat Commun. 2021. PMID: 34535653 Free PMC article.
Targeted therapy for LIMD1-deficient non-small cell lung cancer subtypes.
Davidson K, Grevitt P, Contreras-Gerenas MF, Bridge KS, Hermida M, Shah KM, Mardakheh FK, Stubbs M, Burke R, Casado P, Cutillas PR, Martin SA, Sharp TV. Davidson K, et al. Among authors: mardakheh fk. Cell Death Dis. 2021 Nov 11;12(11):1075. doi: 10.1038/s41419-021-04355-7. Cell Death Dis. 2021. PMID: 34764236 Free PMC article.
TREX reveals proteins that bind to specific RNA regions in living cells.
Dodel M, Guiducci G, Dermit M, Krishnamurthy S, Alard EL, Capraro F, Rekad Z, Stojic L, Mardakheh FK. Dodel M, et al. Among authors: mardakheh fk. Nat Methods. 2024 Mar;21(3):423-434. doi: 10.1038/s41592-024-02181-1. Epub 2024 Feb 19. Nat Methods. 2024. PMID: 38374261 Free PMC article.
An mRNA processing pathway suppresses metastasis by governing translational control from the nucleus.
Navickas A, Asgharian H, Winkler J, Fish L, Garcia K, Markett D, Dodel M, Culbertson B, Miglani S, Joshi T, Yin K, Nguyen P, Zhang S, Stevers N, Hwang HW, Mardakheh F, Goga A, Goodarzi H. Navickas A, et al. Among authors: mardakheh f. Nat Cell Biol. 2023 Jun;25(6):892-903. doi: 10.1038/s41556-023-01141-9. Epub 2023 May 8. Nat Cell Biol. 2023. PMID: 37156909 Free PMC article.
DNA repair deficiency sensitizes lung cancer cells to NAD+ biosynthesis blockade.
Touat M, Sourisseau T, Dorvault N, Chabanon RM, Garrido M, Morel D, Krastev DB, Bigot L, Adam J, Frankum JR, Durand S, Pontoizeau C, Souquère S, Kuo MS, Sauvaigo S, Mardakheh F, Sarasin A, Olaussen KA, Friboulet L, Bouillaud F, Pierron G, Ashworth A, Lombès A, Lord CJ, Soria JC, Postel-Vinay S. Touat M, et al. Among authors: mardakheh f. J Clin Invest. 2018 Apr 2;128(4):1671-1687. doi: 10.1172/JCI90277. Epub 2018 Mar 19. J Clin Invest. 2018. PMID: 29447131 Free PMC article.
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