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Hybrid derivative of cathelicidin and human beta defensin-2 against Gram-positive bacteria: A novel approach for the treatment of bacterial keratitis.
Ting DSJ, Goh ETL, Mayandi V, Busoy JMF, Aung TT, Periayah MH, Nubile M, Mastropasqua L, Said DG, Htoon HM, Barathi VA, Beuerman RW, Lakshminarayanan R, Mohammed I, Dua HS. Ting DSJ, et al. Among authors: beuerman rw. Sci Rep. 2021 Sep 15;11(1):18304. doi: 10.1038/s41598-021-97821-3. Sci Rep. 2021. PMID: 34526600 Free PMC article.
Branched Peptide, B2088, Disrupts the Supramolecular Organization of Lipopolysaccharides and Sensitizes the Gram-negative Bacteria.
Lakshminarayanan R, Tan WX, Aung TT, Goh ET, Muruganantham N, Li J, Chang JY, Dikshit N, Saraswathi P, Lim RR, Kang TS, Balamuralidhar V, Sukumaran B, Verma CS, Sivaraman J, Chaurasia SS, Liu S, Beuerman RW. Lakshminarayanan R, et al. Among authors: beuerman rw. Sci Rep. 2016 May 13;6:25905. doi: 10.1038/srep25905. Sci Rep. 2016. PMID: 27174567 Free PMC article.
Amino acid modified xanthone derivatives: novel, highly promising membrane-active antimicrobials for multidrug-resistant Gram-positive bacterial infections.
Koh JJ, Lin S, Aung TT, Lim F, Zou H, Bai Y, Li J, Lin H, Pang LM, Koh WL, Salleh SM, Lakshminarayanan R, Zhou L, Qiu S, Pervushin K, Verma C, Tan DT, Cao D, Liu S, Beuerman RW. Koh JJ, et al. Among authors: beuerman rw. J Med Chem. 2015 Jan 22;58(2):739-52. doi: 10.1021/jm501285x. Epub 2014 Dec 17. J Med Chem. 2015. PMID: 25474410
Antimicrobial Activity and Cell Selectivity of Synthetic and Biosynthetic Cationic Polymers.
Venkatesh M, Barathi VA, Goh ETL, Anggara R, Fazil MHUT, Ng AJY, Harini S, Aung TT, Fox SJ, Liu S, Yang L, Barkham TMS, Loh XJ, Verma NK, Beuerman RW, Lakshminarayanan R. Venkatesh M, et al. Among authors: beuerman rw. Antimicrob Agents Chemother. 2017 Sep 22;61(10):e00469-17. doi: 10.1128/AAC.00469-17. Print 2017 Oct. Antimicrob Agents Chemother. 2017. PMID: 28784676 Free PMC article.
Protective Action of Linear Polyethylenimine against Staphylococcus aureus Colonization and Exaggerated Inflammation in Vitro and in Vivo.
Mayandi V, Sridhar S, Fazil MHUT, Goh ETL, Htoon HM, Orive G, Choong YK, Saravanan R, Beuerman RW, Barkham TMS, Yang L, Baskaran M, Jhanji V, Loh XJ, Verma NK, Lakshminarayanan R. Mayandi V, et al. Among authors: beuerman rw. ACS Infect Dis. 2019 Aug 9;5(8):1411-1422. doi: 10.1021/acsinfecdis.9b00102. Epub 2019 Jun 5. ACS Infect Dis. 2019. PMID: 31099239
Rational Substitution of ε-Lysine for α-Lysine Enhances the Cell and Membrane Selectivity of Pore-Forming Melittin.
Mayandi V, Xi Q, Leng ET, Koh SK, Jie TY, Barathi VA, Urf Turabe Fazil MH, Somaraju Chalasani ML, Varadarajan J, Ting DSJ, Beuerman RW, Chan LW, Agrawal R, Sebastian TM, Zhou L, Verma NK, Lakshminarayanan R. Mayandi V, et al. Among authors: beuerman rw. J Med Chem. 2020 Apr 9;63(7):3522-3537. doi: 10.1021/acs.jmedchem.9b01846. Epub 2020 Mar 30. J Med Chem. 2020. PMID: 32175733
Mussel-Inspired Durable Antimicrobial Contact Lenses: The Role of Covalent and Noncovalent Attachment of Antimicrobials.
Dhand C, Ong CY, Dwivedi N, Varadarajan J, Halleluyah Periayah M, Jianyang Lim E, Mayandi V, Goh ETL, Najjar RP, Chan LW, Beuerman RW, Foo LL, Loh XJ, Lakshminarayanan R. Dhand C, et al. Among authors: beuerman rw. ACS Biomater Sci Eng. 2020 May 11;6(5):3162-3173. doi: 10.1021/acsbiomaterials.0c00229. Epub 2020 Apr 9. ACS Biomater Sci Eng. 2020. PMID: 33463280
Evaluation of Host Defense Peptide (CaD23)-Antibiotic Interaction and Mechanism of Action: Insights From Experimental and Molecular Dynamics Simulations Studies.
Ting DSJ, Li J, Verma CS, Goh ETL, Nubile M, Mastropasqua L, Said DG, Beuerman RW, Lakshminarayanan R, Mohammed I, Dua HS. Ting DSJ, et al. Among authors: beuerman rw. Front Pharmacol. 2021 Oct 7;12:731499. doi: 10.3389/fphar.2021.731499. eCollection 2021. Front Pharmacol. 2021. PMID: 34690770 Free PMC article.
327 results