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Self-Assembly into Nanoparticles Is Essential for Receptor Mediated Uptake of Therapeutic Antisense Oligonucleotides.
Ezzat K, Aoki Y, Koo T, McClorey G, Benner L, Coenen-Stass A, O'Donovan L, Lehto T, Garcia-Guerra A, Nordin J, Saleh AF, Behlke M, Morris J, Goyenvalle A, Dugovic B, Leumann C, Gordon S, Gait MJ, El-Andaloussi S, Wood MJ. Ezzat K, et al. Nano Lett. 2015 Jul 8;15(7):4364-73. doi: 10.1021/acs.nanolett.5b00490. Epub 2015 Jun 15. Nano Lett. 2015. PMID: 26042553 Free PMC article.
Evidence-Based Clinical Use of Nanoscale Extracellular Vesicles in Nanomedicine.
Fais S, O'Driscoll L, Borras FE, Buzas E, Camussi G, Cappello F, Carvalho J, Cordeiro da Silva A, Del Portillo H, El Andaloussi S, Ficko Trček T, Furlan R, Hendrix A, Gursel I, Kralj-Iglic V, Kaeffer B, Kosanovic M, Lekka ME, Lipps G, Logozzi M, Marcilla A, Sammar M, Llorente A, Nazarenko I, Oliveira C, Pocsfalvi G, Rajendran L, Raposo G, Rohde E, Siljander P, van Niel G, Vasconcelos MH, Yáñez-Mó M, Yliperttula ML, Zarovni N, Zavec AB, Giebel B. Fais S, et al. ACS Nano. 2016 Apr 26;10(4):3886-99. doi: 10.1021/acsnano.5b08015. Epub 2016 Mar 15. ACS Nano. 2016. PMID: 26978483 Review.
Peptides for nucleic acid delivery.
Lehto T, Ezzat K, Wood MJA, El Andaloussi S. Lehto T, et al. Adv Drug Deliv Rev. 2016 Nov 15;106(Pt A):172-182. doi: 10.1016/j.addr.2016.06.008. Epub 2016 Jun 25. Adv Drug Deliv Rev. 2016. PMID: 27349594 Free article. Review.
Delivery is key: lessons learnt from developing splice-switching antisense therapies.
Godfrey C, Desviat LR, Smedsrød B, Piétri-Rouxel F, Denti MA, Disterer P, Lorain S, Nogales-Gadea G, Sardone V, Anwar R, El Andaloussi S, Lehto T, Khoo B, Brolin C, van Roon-Mom WM, Goyenvalle A, Aartsma-Rus A, Arechavala-Gomeza V. Godfrey C, et al. EMBO Mol Med. 2017 May;9(5):545-557. doi: 10.15252/emmm.201607199. EMBO Mol Med. 2017. PMID: 28289078 Free PMC article. Review.
Functional Delivery of Lipid-Conjugated siRNA by Extracellular Vesicles.
O'Loughlin AJ, Mäger I, de Jong OG, Varela MA, Schiffelers RM, El Andaloussi S, Wood MJA, Vader P. O'Loughlin AJ, et al. Mol Ther. 2017 Jul 5;25(7):1580-1587. doi: 10.1016/j.ymthe.2017.03.021. Epub 2017 Apr 6. Mol Ther. 2017. PMID: 28392161 Free PMC article.
Methodological Guidelines to Study Extracellular Vesicles.
Coumans FAW, Brisson AR, Buzas EI, Dignat-George F, Drees EEE, El-Andaloussi S, Emanueli C, Gasecka A, Hendrix A, Hill AF, Lacroix R, Lee Y, van Leeuwen TG, Mackman N, Mäger I, Nolan JP, van der Pol E, Pegtel DM, Sahoo S, Siljander PRM, Sturk G, de Wever O, Nieuwland R. Coumans FAW, et al. Circ Res. 2017 May 12;120(10):1632-1648. doi: 10.1161/CIRCRESAHA.117.309417. Circ Res. 2017. PMID: 28495994 Review.
131 results