Justice J - Search Results

1

Extending human healthspan and longevity: a symposium report.

DeVito LM, Barzilai N, Cuervo AM, Niedernhofer LJ, Milman S, Levine M, Promislow D, Ferrucci L, Kuchel GA, Mannick J, Justice J, Gonzales MM, Kirkland JL, Cohen P, Campisi J. DeVito LM, et al. Among authors: justice j. Ann N Y Acad Sci. 2022 Jan;1507(1):70-83. doi: 10.1111/nyas.14681. Epub 2021 Sep 8. Ann N Y Acad Sci. 2022. PMID: 34498278 Free PMC article. Review.

2

Frameworks for Proof-of-Concept Clinical Trials of Interventions That Target Fundamental Aging Processes.

Justice J, Miller JD, Newman JC, Hashmi SK, Halter J, Austad SN, Barzilai N, Kirkland JL. Justice J, et al. J Gerontol A Biol Sci Med Sci. 2016 Nov;71(11):1415-1423. doi: 10.1093/gerona/glw126. Epub 2016 Aug 16. J Gerontol A Biol Sci Med Sci. 2016. PMID: 27535966 Free PMC article.

3

Evaluating Health Span in Preclinical Models of Aging and Disease: Guidelines, Challenges, and Opportunities for Geroscience.

Huffman DM, Justice JN, Stout MB, Kirkland JL, Barzilai N, Austad SN. Huffman DM, et al. J Gerontol A Biol Sci Med Sci. 2016 Nov;71(11):1395-1406. doi: 10.1093/gerona/glw106. Epub 2016 Aug 16. J Gerontol A Biol Sci Med Sci. 2016. PMID: 27535967 Free PMC article.

4

Physiological Aging: Links Among Adipose Tissue Dysfunction, Diabetes, and Frailty.

Stout MB, Justice JN, Nicklas BJ, Kirkland JL. Stout MB, et al. Among authors: justice jn. Physiology (Bethesda). 2017 Jan;32(1):9-19. doi: 10.1152/physiol.00012.2016. Physiology (Bethesda). 2017. PMID: 27927801 Free PMC article. Review.

5

Cellular Senescence Biomarker p16INK4a+ Cell Burden in Thigh Adipose is Associated With Poor Physical Function in Older Women.

Justice JN, Gregory H, Tchkonia T, LeBrasseur NK, Kirkland JL, Kritchevsky SB, Nicklas BJ. Justice JN, et al. J Gerontol A Biol Sci Med Sci. 2018 Jun 14;73(7):939-945. doi: 10.1093/gerona/glx134. J Gerontol A Biol Sci Med Sci. 2018. PMID: 28658942 Free PMC article.

6

A framework for selection of blood-based biomarkers for geroscience-guided clinical trials: report from the TAME Biomarkers Workgroup.

Justice JN, Ferrucci L, Newman AB, Aroda VR, Bahnson JL, Divers J, Espeland MA, Marcovina S, Pollak MN, Kritchevsky SB, Barzilai N, Kuchel GA. Justice JN, et al. Geroscience. 2018 Dec;40(5-6):419-436. doi: 10.1007/s11357-018-0042-y. Epub 2018 Aug 27. Geroscience. 2018. PMID: 30151729 Free PMC article. Review.

7

Senolytics in idiopathic pulmonary fibrosis: Results from a first-in-human, open-label, pilot study.

Justice JN, Nambiar AM, Tchkonia T, LeBrasseur NK, Pascual R, Hashmi SK, Prata L, Masternak MM, Kritchevsky SB, Musi N, Kirkland JL. Justice JN, et al. EBioMedicine. 2019 Feb;40:554-563. doi: 10.1016/j.ebiom.2018.12.052. Epub 2019 Jan 5. EBioMedicine. 2019. PMID: 30616998 Free PMC article. Clinical Trial.

8

Development of Clinical Trials to Extend Healthy Lifespan.

Justice JN, Niedernhofer L, Robbins PD, Aroda VR, Espeland MA, Kritchevsky SB, Kuchel GA, Barzilai N. Justice JN, et al. Cardiovasc Endocrinol Metab. 2018 Dec;7(4):80-83. doi: 10.1097/XCE.0000000000000159. Cardiovasc Endocrinol Metab. 2018. PMID: 30906924 Free PMC article.

9

A geroscience perspective on immune resilience and infectious diseases: a potential case for metformin.

Justice JN, Gubbi S, Kulkarni AS, Bartley JM, Kuchel GA, Barzilai N. Justice JN, et al. Geroscience. 2021 Jun;43(3):1093-1112. doi: 10.1007/s11357-020-00261-6. Epub 2020 Sep 9. Geroscience. 2021. PMID: 32902818 Free PMC article. Review.

10

Orally-active, clinically-translatable senolytics restore α-Klotho in mice and humans.

Zhu Y, Prata LGPL, Gerdes EOW, Netto JME, Pirtskhalava T, Giorgadze N, Tripathi U, Inman CL, Johnson KO, Xue A, Palmer AK, Chen T, Schaefer K, Justice JN, Nambiar AM, Musi N, Kritchevsky SB, Chen J, Khosla S, Jurk D, Schafer MJ, Tchkonia T, Kirkland JL. Zhu Y, et al. Among authors: justice jn. EBioMedicine. 2022 Mar;77:103912. doi: 10.1016/j.ebiom.2022.103912. Epub 2022 Mar 13. EBioMedicine. 2022. PMID: 35292270 Free PMC article.

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