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Characterisation of Ppy-lineage cells clarifies the functional heterogeneity of pancreatic beta cells in mice.
Fukaishi T, Nakagawa Y, Fukunaka A, Sato T, Hara A, Nakao K, Saito M, Kohno K, Miyatsuka T, Tamaki M, Matsuhisa M, Matsuoka TA, Yamada T, Watada H, Fujitani Y. Fukaishi T, et al. Among authors: yamada t. Diabetologia. 2021 Dec;64(12):2803-2816. doi: 10.1007/s00125-021-05560-x. Epub 2021 Sep 9. Diabetologia. 2021. PMID: 34498099 Free PMC article.
A case of generalized lipodystrophy-associated progeroid syndrome treated by leptin replacement with short and long-term monitoring of the metabolic and endocrine profiles.
Fukaishi T, Minami I, Masuda S, Miyachi Y, Tsujimoto K, Izumiyama H, Hashimoto K, Yoshida M, Takahashi S, Kashimada K, Morio T, Kosaki K, Maezawa Y, Yokote K, Yoshimoto T, Yamada T. Fukaishi T, et al. Among authors: yamada t. Endocr J. 2020 Feb 28;67(2):211-218. doi: 10.1507/endocrj.EJ19-0226. Epub 2019 Nov 8. Endocr J. 2020. PMID: 31708526 Free article.
Regulation of pancreatic beta cell mass by neuronal signals from the liver.
Imai J, Katagiri H, Yamada T, Ishigaki Y, Suzuki T, Kudo H, Uno K, Hasegawa Y, Gao J, Kaneko K, Ishihara H, Niijima A, Nakazato M, Asano T, Minokoshi Y, Oka Y. Imai J, et al. Among authors: yamada t. Science. 2008 Nov 21;322(5905):1250-4. doi: 10.1126/science.1163971. Science. 2008. PMID: 19023081
Bach1 deficiency protects pancreatic β-cells from oxidative stress injury.
Kondo K, Ishigaki Y, Gao J, Yamada T, Imai J, Sawada S, Muto A, Oka Y, Igarashi K, Katagiri H. Kondo K, et al. Among authors: yamada t. Am J Physiol Endocrinol Metab. 2013 Sep 1;305(5):E641-8. doi: 10.1152/ajpendo.00120.2013. Epub 2013 Jul 23. Am J Physiol Endocrinol Metab. 2013. PMID: 23880309 Free article.
MicroRNAs 106b and 222 Improve Hyperglycemia in a Mouse Model of Insulin-Deficient Diabetes via Pancreatic β-Cell Proliferation.
Tsukita S, Yamada T, Takahashi K, Munakata Y, Hosaka S, Takahashi H, Gao J, Shirai Y, Kodama S, Asai Y, Sugisawa T, Chiba Y, Kaneko K, Uno K, Sawada S, Imai J, Katagiri H. Tsukita S, et al. Among authors: yamada t. EBioMedicine. 2017 Feb;15:163-172. doi: 10.1016/j.ebiom.2016.12.002. Epub 2016 Dec 7. EBioMedicine. 2017. PMID: 27974246 Free PMC article.
Neuronal signals regulate obesity induced β-cell proliferation by FoxM1 dependent mechanism.
Yamamoto J, Imai J, Izumi T, Takahashi H, Kawana Y, Takahashi K, Kodama S, Kaneko K, Gao J, Uno K, Sawada S, Asano T, Kalinichenko VV, Susaki EA, Kanzaki M, Ueda HR, Ishigaki Y, Yamada T, Katagiri H. Yamamoto J, et al. Among authors: yamada t. Nat Commun. 2017 Dec 5;8(1):1930. doi: 10.1038/s41467-017-01869-7. Nat Commun. 2017. PMID: 29208957 Free PMC article.
Islet cell dedifferentiation is a pathologic mechanism of long-standing progression of type 2 diabetes.
Amo-Shiinoki K, Tanabe K, Hoshii Y, Matsui H, Harano R, Fukuda T, Takeuchi T, Bouchi R, Takagi T, Hatanaka M, Takeda K, Okuya S, Nishimura W, Kudo A, Tanaka S, Tanabe M, Akashi T, Yamada T, Ogawa Y, Ikeda E, Nagano H, Tanizawa Y. Amo-Shiinoki K, et al. Among authors: yamada t. JCI Insight. 2021 Jan 11;6(1):e143791. doi: 10.1172/jci.insight.143791. JCI Insight. 2021. PMID: 33427207 Free PMC article.
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