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First-in-Human Evaluation of Positron Emission Tomography/Computed Tomography With [18F]FB(ePEG12)12-Exendin-4: A Phase 1 Clinical Study Targeting GLP-1 Receptor Expression Cells in Pancreas.
Fujimoto H, Fujita N, Hamamatsu K, Murakami T, Nakamoto Y, Saga T, Ishimori T, Shimizu Y, Watanabe H, Sano K, Harada N, Nakamura H, Toyoda K, Kimura H, Nakagawa S, Hirai M, Murakami A, Ono M, Togashi K, Saji H, Inagaki N. Fujimoto H, et al. Among authors: fujita n. Front Endocrinol (Lausanne). 2021 Aug 19;12:717101. doi: 10.3389/fendo.2021.717101. eCollection 2021. Front Endocrinol (Lausanne). 2021. PMID: 34489868 Free PMC article. Clinical Trial.
Synthesis and biological evaluation of an 111In-labeled exendin-4 derivative as a single-photon emission computed tomography probe for imaging pancreatic β-cells.
Kimura H, Fujita N, Kanbe K, Matsuda H, Watanabe H, Arimitsu K, Fujimoto H, Hamamatsu K, Yagi Y, Ono M, Inagaki N, Saji H. Kimura H, et al. Among authors: fujita n. Bioorg Med Chem. 2017 Oct 15;25(20):5772-5778. doi: 10.1016/j.bmc.2017.09.005. Epub 2017 Sep 7. Bioorg Med Chem. 2017. PMID: 28927802
Evaluation of 18F-labeled exendin(9-39) derivatives targeting glucagon-like peptide-1 receptor for pancreatic β-cell imaging.
Kimura H, Ogawa Y, Fujimoto H, Mukai E, Kawashima H, Arimitsu K, Toyoda K, Fujita N, Yagi Y, Hamamatsu K, Murakami T, Murakami A, Ono M, Nakamoto Y, Togashi K, Inagaki N, Saji H. Kimura H, et al. Among authors: fujita n. Bioorg Med Chem. 2018 Jan 15;26(2):463-469. doi: 10.1016/j.bmc.2017.12.007. Epub 2017 Dec 5. Bioorg Med Chem. 2018. PMID: 29273416
Noninvasive longitudinal quantification of β-cell mass with [111In]-labeled exendin-4.
Fujita N, Fujimoto H, Hamamatsu K, Murakami T, Kimura H, Toyoda K, Saji H, Inagaki N. Fujita N, et al. FASEB J. 2019 Nov;33(11):11836-11844. doi: 10.1096/fj.201900555RR. Epub 2019 Aug 1. FASEB J. 2019. PMID: 31370679 Free PMC article.
This technique successfully demonstrated longitudinal changes in BCM in NOD mice before and after onset of hyperglycemia.-Fujita, N., Fujimoto, H., Hamamatsu, K., Murakami, T., Kimura, H., Toyoda, K., Saji, H., Inagaki, N. ...
This technique successfully demonstrated longitudinal changes in BCM in NOD mice before and after onset of hyperglycemia.-Fujita, …
Distinctive detection of insulinoma using [18F]FB(ePEG12)12-exendin-4 PET/CT.
Murakami T, Fujimoto H, Hamamatsu K, Yamauchi Y, Kodama Y, Fujita N, Fujikura J, Shimizu Y, Nakamoto Y, Kimura H, Saji H, Inagaki N. Murakami T, et al. Among authors: fujita n. Sci Rep. 2021 Jul 22;11(1):15014. doi: 10.1038/s41598-021-94595-6. Sci Rep. 2021. PMID: 34294854 Free PMC article.
Noninvasive Evaluation of GIP Effects on β-Cell Mass Under High-Fat Diet.
Kiyobayashi S, Murakami T, Harada N, Fujimoto H, Murata Y, Fujita N, Hamamatsu K, Ikeguchi-Ogura E, Hatoko T, Lu X, Yamane S, Inagaki N. Kiyobayashi S, et al. Among authors: fujita n. Front Endocrinol (Lausanne). 2022 Jul 12;13:921125. doi: 10.3389/fendo.2022.921125. eCollection 2022. Front Endocrinol (Lausanne). 2022. PMID: 35909510 Free PMC article.
2,584 results