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Single-cell and bulk transcriptome sequencing identifies two epithelial tumor cell states and refines the consensus molecular classification of colorectal cancer.
Joanito I, Wirapati P, Zhao N, Nawaz Z, Yeo G, Lee F, Eng CLP, Macalinao DC, Kahraman M, Srinivasan H, Lakshmanan V, Verbandt S, Tsantoulis P, Gunn N, Venkatesh PN, Poh ZW, Nahar R, Oh HLJ, Loo JM, Chia S, Cheow LF, Cheruba E, Wong MT, Kua L, Chua C, Nguyen A, Golovan J, Gan A, Lim WJ, Guo YA, Yap CK, Tay B, Hong Y, Chong DQ, Chok AY, Park WY, Han S, Chang MH, Seow-En I, Fu C, Mathew R, Toh EL, Hong LZ, Skanderup AJ, DasGupta R, Ong CJ, Lim KH, Tan EKW, Koo SL, Leow WQ, Tejpar S, Prabhakar S, Tan IB. Joanito I, et al. Among authors: eng clp. Nat Genet. 2022 Jul;54(7):963-975. doi: 10.1038/s41588-022-01100-4. Epub 2022 Jun 30. Nat Genet. 2022. PMID: 35773407 Free PMC article.
What Is Your Diagnosis?
Dawes ME, Britt LG, Jones BT, Shuck KK, Eng CL, Memarzadeh A, Ondrak JD. Dawes ME, et al. Among authors: eng cl. J Am Vet Med Assoc. 2022 Feb 10;260(4):401-403. doi: 10.2460/javma.20.11.0631. J Am Vet Med Assoc. 2022. PMID: 34986117 Free article. No abstract available.
Integration of spatial and single-cell transcriptomic data elucidates mouse organogenesis.
Lohoff T, Ghazanfar S, Missarova A, Koulena N, Pierson N, Griffiths JA, Bardot ES, Eng CL, Tyser RCV, Argelaguet R, Guibentif C, Srinivas S, Briscoe J, Simons BD, Hadjantonakis AK, Göttgens B, Reik W, Nichols J, Cai L, Marioni JC. Lohoff T, et al. Among authors: eng cl. Nat Biotechnol. 2022 Jan;40(1):74-85. doi: 10.1038/s41587-021-01006-2. Epub 2021 Sep 6. Nat Biotechnol. 2022. PMID: 34489600 Free PMC article.
Integrated spatial genomics reveals global architecture of single nuclei.
Takei Y, Yun J, Zheng S, Ollikainen N, Pierson N, White J, Shah S, Thomassie J, Suo S, Eng CL, Guttman M, Yuan GC, Cai L. Takei Y, et al. Among authors: eng cl. Nature. 2021 Feb;590(7845):344-350. doi: 10.1038/s41586-020-03126-2. Epub 2021 Jan 27. Nature. 2021. PMID: 33505024 Free PMC article.
Multiple Myeloma DREAM Challenge reveals epigenetic regulator PHF19 as marker of aggressive disease.
Mason MJ, Schinke C, Eng CLP, Towfic F, Gruber F, Dervan A, White BS, Pratapa A, Guan Y, Chen H, Cui Y, Li B, Yu T, Chaibub Neto E, Mavrommatis K, Ortiz M, Lyzogubov V, Bisht K, Dai HY, Schmitz F, Flynt E, Dan Rozelle, Danziger SA, Ratushny A; Multiple Myeloma DREAM Consortium; Dalton WS, Goldschmidt H, Avet-Loiseau H, Samur M, Hayete B, Sonneveld P, Shain KH, Munshi N, Auclair D, Hose D, Morgan G, Trotter M, Bassett D, Goke J, Walker BA, Thakurta A, Guinney J. Mason MJ, et al. Among authors: eng clp. Leukemia. 2020 Jul;34(7):1866-1874. doi: 10.1038/s41375-020-0742-z. Epub 2020 Feb 14. Leukemia. 2020. PMID: 32060406 Free PMC article.
Transcriptome-scale super-resolved imaging in tissues by RNA seqFISH.
Eng CL, Lawson M, Zhu Q, Dries R, Koulena N, Takei Y, Yun J, Cronin C, Karp C, Yuan GC, Cai L. Eng CL, et al. Nature. 2019 Apr;568(7751):235-239. doi: 10.1038/s41586-019-1049-y. Epub 2019 Mar 25. Nature. 2019. PMID: 30911168 Free PMC article.
Dynamics and Spatial Genomics of the Nascent Transcriptome by Intron seqFISH.
Shah S, Takei Y, Zhou W, Lubeck E, Yun J, Eng CL, Koulena N, Cronin C, Karp C, Liaw EJ, Amin M, Cai L. Shah S, et al. Among authors: eng cl. Cell. 2018 Jul 12;174(2):363-376.e16. doi: 10.1016/j.cell.2018.05.035. Epub 2018 Jun 7. Cell. 2018. PMID: 29887381 Free PMC article.
Profiling the transcriptome with RNA SPOTs.
Eng CL, Shah S, Thomassie J, Cai L. Eng CL, et al. Nat Methods. 2017 Dec;14(12):1153-1155. doi: 10.1038/nmeth.4500. Epub 2017 Nov 13. Nat Methods. 2017. PMID: 29131163 Free PMC article.
17 results