Webb BM - Search Results

1

TGF-β/activin signaling promotes CDK7 inhibitor resistance in triple-negative breast cancer cells through upregulation of multidrug transporters.

Webb BM, Bryson BL, Williams-Medina E, Bobbitt JR, Seachrist DD, Anstine LJ, Keri RA. Webb BM, et al. J Biol Chem. 2021 Oct;297(4):101162. doi: 10.1016/j.jbc.2021.101162. Epub 2021 Sep 2. J Biol Chem. 2021. PMID: 34481843 Free PMC article.

2

Bromodomain and Extraterminal Protein Inhibition Blocks Growth of Triple-negative Breast Cancers through the Suppression of Aurora Kinases.

Sahni JM, Gayle SS, Bonk KL, Vite LC, Yori JL, Webb B, Ramos EK, Seachrist DD, Landis MD, Chang JC, Bradner JE, Keri RA. Sahni JM, et al. J Biol Chem. 2016 Nov 4;291(45):23756-23768. doi: 10.1074/jbc.M116.738666. Epub 2016 Sep 20. J Biol Chem. 2016. PMID: 27650498 Free PMC article.

3

Mitotic Vulnerability in Triple-Negative Breast Cancer Associated with LIN9 Is Targetable with BET Inhibitors.

Sahni JM, Gayle SS, Webb BM, Weber-Bonk KL, Seachrist DD, Singh S, Sizemore ST, Restrepo NA, Bebek G, Scacheri PC, Varadan V, Summers MK, Keri RA. Sahni JM, et al. Among authors: webb bm. Cancer Res. 2017 Oct 1;77(19):5395-5408. doi: 10.1158/0008-5472.CAN-17-1571. Epub 2017 Aug 14. Cancer Res. 2017. PMID: 28807940 Free PMC article.

4

Targeting BCL-xL improves the efficacy of bromodomain and extra-terminal protein inhibitors in triple-negative breast cancer by eliciting the death of senescent cells.

Gayle SS, Sahni JM, Webb BM, Weber-Bonk KL, Shively MS, Spina R, Bar EE, Summers MK, Keri RA. Gayle SS, et al. Among authors: webb bm. J Biol Chem. 2019 Jan 18;294(3):875-886. doi: 10.1074/jbc.RA118.004712. Epub 2018 Nov 27. J Biol Chem. 2019. PMID: 30482844 Free PMC article.

5

KLF4 defines the efficacy of the epidermal growth factor receptor inhibitor, erlotinib, in triple-negative breast cancer cells by repressing the EGFR gene.

Roberts MS, Anstine LJ, Finke VS, Bryson BL, Webb BM, Weber-Bonk KL, Seachrist DD, Majmudar PR, Keri RA. Roberts MS, et al. Among authors: webb bm. Breast Cancer Res. 2020 Jun 18;22(1):66. doi: 10.1186/s13058-020-01305-7. Breast Cancer Res. 2020. PMID: 32552913 Free PMC article.

6

The transcriptional repressor BCL11A promotes breast cancer metastasis.

Seachrist DD, Hannigan MM, Ingles NN, Webb BM, Weber-Bonk KL, Yu P, Bebek G, Singh S, Sizemore ST, Varadan V, Licatalosi DD, Keri RA. Seachrist DD, et al. Among authors: webb bm. J Biol Chem. 2020 Aug 14;295(33):11707-11719. doi: 10.1074/jbc.RA120.014018. Epub 2020 Jun 23. J Biol Chem. 2020. PMID: 32576660 Free PMC article.

7

Correction: Bromodomain and extraterminal protein inhibition blocks growth of triple-negative breast cancers through the suppression of aurora kinases.

Sahni JM, Gayle SS, Bonk KLW, Vite LC, Yori JL, Webb B, Ramos EK, Seachrist DD, Landis MD, Chang JC, Bradner JE, Keri RA. Sahni JM, et al. J Biol Chem. 2020 Jul 3;295(27):9266. doi: 10.1074/jbc.AAC120.014699. J Biol Chem. 2020. PMID: 32620694 Free PMC article. No abstract available.

8

[No title available]

[No authors listed] [No authors listed] PMID: 33516519

9

TLE3 Sustains Luminal Breast Cancer Lineage Fidelity to Suppress Metastasis.

Anstine LJ, Majmudar PR, Aponte A, Singh S, Zhao R, Weber-Bonk KL, Abdul-Karim FW, Valentine M, Seachrist DD, Grennel-Nickelson KE, Cuellar-Vite L, Sizemore GM, Sizemore ST, Webb BM, Thompson CL, Keri RA. Anstine LJ, et al. Among authors: webb bm. Cancer Res. 2023 Apr 4;83(7):997-1015. doi: 10.1158/0008-5472.CAN-22-3133. Cancer Res. 2023. PMID: 36696357 Free PMC article.

10

Disruption of CDK7 signaling leads to catastrophic chromosomal instability coupled with a loss of condensin-mediated chromatin compaction.

Piemonte KM, Webb BM, Bobbitt JR, Majmudar PR, Cuellar-Vite L, Bryson BL, Latina NC, Seachrist DD, Keri RA. Piemonte KM, et al. Among authors: webb bm. J Biol Chem. 2023 Jul;299(7):104834. doi: 10.1016/j.jbc.2023.104834. Epub 2023 May 17. J Biol Chem. 2023. PMID: 37201585 Free PMC article.

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