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Single allele loss-of-function mutations select and sculpt conditional cooperative networks in breast cancer.
Schachter NF, Adams JR, Skowron P, Kozma KJ, Lee CA, Raghuram N, Yang J, Loch AJ, Wang W, Kucharczuk A, Wright KL, Quintana RM, An Y, Dotzko D, Gorman JL, Wojtal D, Shah JS, Leon-Gomez P, Pellecchia G, Dupuy AJ, Perou CM, Ben-Porath I, Karni R, Zacksenhaus E, Woodgett JR, Done SJ, Garzia L, Sorana Morrissy A, Reimand J, Taylor MD, Egan SE. Schachter NF, et al. Among authors: woodgett jr. Nat Commun. 2021 Sep 2;12(1):5238. doi: 10.1038/s41467-021-25467-w. Nat Commun. 2021. PMID: 34475389 Free PMC article.
A Hematogenous Route for Medulloblastoma Leptomeningeal Metastases.
Garzia L, Kijima N, Morrissy AS, De Antonellis P, Guerreiro-Stucklin A, Holgado BL, Wu X, Wang X, Parsons M, Zayne K, Manno A, Kuzan-Fischer C, Nor C, Donovan LK, Liu J, Qin L, Garancher A, Liu KW, Mansouri S, Luu B, Thompson YY, Ramaswamy V, Peacock J, Farooq H, Skowron P, Shih DJH, Li A, Ensan S, Robbins CS, Cybulsky M, Mitra S, Ma Y, Moore R, Mungall A, Cho YJ, Weiss WA, Chan JA, Hawkins CE, Massimino M, Jabado N, Zapotocky M, Sumerauer D, Bouffet E, Dirks P, Tabori U, Sorensen PHB, Brastianos PK, Aldape K, Jones SJM, Marra MA, Woodgett JR, Wechsler-Reya RJ, Fults DW, Taylor MD. Garzia L, et al. Among authors: woodgett jr. Cell. 2018 Feb 22;172(5):1050-1062.e14. doi: 10.1016/j.cell.2018.01.038. Cell. 2018. PMID: 29474906 Free PMC article.
Identification of CDC25 as a Common Therapeutic Target for Triple-Negative Breast Cancer.
Liu JC, Granieri L, Shrestha M, Wang DY, Vorobieva I, Rubie EA, Jones R, Ju Y, Pellecchia G, Jiang Z, Palmerini CA, Ben-David Y, Egan SE, Woodgett JR, Bader GD, Datti A, Zacksenhaus E. Liu JC, et al. Among authors: woodgett jr. Cell Rep. 2018 Apr 3;23(1):112-126. doi: 10.1016/j.celrep.2018.03.039. Cell Rep. 2018. PMID: 29617654 Free PMC article.
Distinct shared and compartment-enriched oncogenic networks drive primary versus metastatic breast cancer.
Jiang Z, Ju Y, Ali A, Chung PED, Skowron P, Wang DY, Shrestha M, Li H, Liu JC, Vorobieva I, Ghanbari-Azarnier R, Mwewa E, Koritzinsky M, Ben-David Y, Woodgett JR, Perou CM, Dupuy A, Bader GD, Egan SE, Taylor MD, Zacksenhaus E. Jiang Z, et al. Among authors: woodgett jr. Nat Commun. 2023 Jul 18;14(1):4313. doi: 10.1038/s41467-023-39935-y. Nat Commun. 2023. PMID: 37463901 Free PMC article.
Presenilin mutations associated with Alzheimer disease cause defective intracellular trafficking of beta-catenin, a component of the presenilin protein complex.
Nishimura M, Yu G, Levesque G, Zhang DM, Ruel L, Chen F, Milman P, Holmes E, Liang Y, Kawarai T, Jo E, Supala A, Rogaeva E, Xu DM, Janus C, Levesque L, Bi Q, Duthie M, Rozmahel R, Mattila K, Lannfelt L, Westaway D, Mount HT, Woodgett J, St George-Hyslop P, et al. Nishimura M, et al. Nat Med. 1999 Feb;5(2):164-9. doi: 10.1038/5526. Nat Med. 1999. PMID: 9930863
296 results