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Single allele loss-of-function mutations select and sculpt conditional cooperative networks in breast cancer.
Nat Commun. 2021 Sep 2;12(1):5238. doi: 10.1038/s41467-021-25467-w.
Nat Commun. 2021.
PMID: 34475389
Free PMC article.
Cooperation between Pik3ca and p53 mutations in mouse mammary tumor formation.
Adams JR, Xu K, Liu JC, Agamez NM, Loch AJ, Wong RG, Wang W, Wright KL, Lane TF, Zacksenhaus E, Egan SE.
Adams JR, et al. Among authors: loch aj.
Cancer Res. 2011 Apr 1;71(7):2706-17. doi: 10.1158/0008-5472.CAN-10-0738. Epub 2011 Feb 15.
Cancer Res. 2011.
PMID: 21324922
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Lunatic fringe deficiency cooperates with the Met/Caveolin gene amplicon to induce basal-like breast cancer.
Xu K, Usary J, Kousis PC, Prat A, Wang DY, Adams JR, Wang W, Loch AJ, Deng T, Zhao W, Cardiff RD, Yoon K, Gaiano N, Ling V, Beyene J, Zacksenhaus E, Gridley T, Leong WL, Guidos CJ, Perou CM, Egan SE.
Xu K, et al. Among authors: loch aj.
Cancer Cell. 2012 May 15;21(5):626-641. doi: 10.1016/j.ccr.2012.03.041.
Cancer Cell. 2012.
PMID: 22624713
Free PMC article.
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Ras Signaling Is a Key Determinant for Metastatic Dissemination and Poor Survival of Luminal Breast Cancer Patients.
Wright KL, Adams JR, Liu JC, Loch AJ, Wong RG, Jo CE, Beck LA, Santhanam DR, Weiss L, Mei X, Lane TF, Koralov SB, Done SJ, Woodgett JR, Zacksenhaus E, Hu P, Egan SE.
Wright KL, et al. Among authors: loch aj.
Cancer Res. 2015 Nov 15;75(22):4960-72. doi: 10.1158/0008-5472.CAN-14-2992. Epub 2015 Sep 23.
Cancer Res. 2015.
PMID: 26400062
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Cdh1 and Pik3ca Mutations Cooperate to Induce Immune-Related Invasive Lobular Carcinoma of the Breast.
An Y, Adams JR, Hollern DP, Zhao A, Chang SG, Gams MS, Chung PED, He X, Jangra R, Shah JS, Yang J, Beck LA, Raghuram N, Kozma KJ, Loch AJ, Wang W, Fan C, Done SJ, Zacksenhaus E, Guidos CJ, Perou CM, Egan SE.
An Y, et al. Among authors: loch aj.
Cell Rep. 2018 Oct 16;25(3):702-714.e6. doi: 10.1016/j.celrep.2018.09.056.
Cell Rep. 2018.
PMID: 30332649
Free PMC article.
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Identification of RSK and TTK as Modulators of Blood Vessel Morphogenesis Using an Embryonic Stem Cell-Based Vascular Differentiation Assay.
Hammoud L, Adams JR, Loch AJ, Marcellus RC, Uehling DE, Aman A, Fladd C, McKee TD, Jo CEB, Al-Awar R, Egan SE, Rossant J.
Hammoud L, et al. Among authors: loch aj.
Stem Cell Reports. 2016 Oct 11;7(4):787-801. doi: 10.1016/j.stemcr.2016.08.004. Epub 2016 Sep 8.
Stem Cell Reports. 2016.
PMID: 27618721
Free PMC article.
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Jagged1 is the major regulator of Notch-dependent cell fate in proximal airways.
Zhang S, Loch AJ, Radtke F, Egan SE, Xu K.
Zhang S, et al. Among authors: loch aj.
Dev Dyn. 2013 Jun;242(6):678-86. doi: 10.1002/dvdy.23965. Epub 2013 Apr 29.
Dev Dyn. 2013.
PMID: 23526493
Free article.
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Elevated expression of wildtype RhoC promotes ErbB2- and Pik3ca-induced mammary tumor formation.
Raghuram N, Temel EI, Kawamata T, Kozma KJ, Loch AJ, Wang W, Adams JR, Muller WJ, Egan SE.
Raghuram N, et al. Among authors: loch aj.
Breast Cancer Res. 2024 May 28;26(1):86. doi: 10.1186/s13058-024-01842-5.
Breast Cancer Res. 2024.
PMID: 38807216
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