Marreddy RKR - Search Results

1

Ebselen Not Only Inhibits Clostridioides difficile Toxins but Displays Redox-Associated Cellular Killing.

Marreddy RKR, Olaitan AO, May JN, Dong M, Hurdle JG. Marreddy RKR, et al. Microbiol Spectr. 2021 Oct 31;9(2):e0044821. doi: 10.1128/Spectrum.00448-21. Epub 2021 Sep 1. Microbiol Spectr. 2021. PMID: 34468187 Free PMC article.

2

New β-lactam - Tetramic acid hybrids show promising antibacterial activities.

Cherian PT, Cheramie MN, Marreddy RKR, Fernando DM, Hurdle JG, Lee RE. Cherian PT, et al. Among authors: marreddy rkr. Bioorg Med Chem Lett. 2018 Oct 1;28(18):3105-3112. doi: 10.1016/j.bmcl.2018.07.018. Epub 2018 Jul 17. Bioorg Med Chem Lett. 2018. PMID: 30097368

3

The Fatty Acid Synthesis Protein Enoyl-ACP Reductase II (FabK) is a Target for Narrow-Spectrum Antibacterials for Clostridium difficile Infection.

Marreddy RKR, Wu X, Sapkota M, Prior AM, Jones JA, Sun D, Hevener KE, Hurdle JG. Marreddy RKR, et al. ACS Infect Dis. 2019 Feb 8;5(2):208-217. doi: 10.1021/acsinfecdis.8b00205. Epub 2018 Dec 13. ACS Infect Dis. 2019. PMID: 30501172 Free PMC article.

4

Small-Molecule Inhibition of the C. difficile FAS-II Enzyme, FabK, Results in Selective Activity.

Jones JA, Prior AM, Marreddy RKR, Wahrmund RD, Hurdle JG, Sun D, Hevener KE. Jones JA, et al. Among authors: marreddy rkr. ACS Chem Biol. 2019 Jul 19;14(7):1528-1535. doi: 10.1021/acschembio.9b00293. Epub 2019 Jun 26. ACS Chem Biol. 2019. PMID: 31184849 Free PMC article.

5

The early stage peptidoglycan biosynthesis Mur enzymes are antibacterial and antisporulation drug targets for recurrent Clostridioides difficile infection.

Sapkota M, Marreddy RKR, Wu X, Kumar M, Hurdle JG. Sapkota M, et al. Among authors: marreddy rkr. Anaerobe. 2020 Feb;61:102129. doi: 10.1016/j.anaerobe.2019.102129. Epub 2019 Nov 21. Anaerobe. 2020. PMID: 31760080 Free PMC article.

6

C. difficile intoxicates neurons and pericytes to drive neurogenic inflammation.

Manion J, Musser MA, Kuziel GA, Liu M, Shepherd A, Wang S, Lee PG, Zhao L, Zhang J, Marreddy RKR, Goldsmith JD, Yuan K, Hurdle JG, Gerhard R, Jin R, Rakoff-Nahoum S, Rao M, Dong M. Manion J, et al. Among authors: marreddy rkr. Nature. 2023 Oct;622(7983):611-618. doi: 10.1038/s41586-023-06607-2. Epub 2023 Sep 12. Nature. 2023. PMID: 37699522

7

Biophysical characterization of E. coli TolC interaction with the known blocker hexaamminecobalt.

Gilardi A, Bhamidimarri SP, Brönstrup M, Bilitewski U, Marreddy RKR, Pos KM, Benier L, Gribbon P, Winterhalter M, Windshügel B. Gilardi A, et al. Among authors: marreddy rkr. Biochim Biophys Acta Gen Subj. 2017 Nov;1861(11 Pt A):2702-2709. doi: 10.1016/j.bbagen.2017.07.014. Epub 2017 Jul 23. Biochim Biophys Acta Gen Subj. 2017. PMID: 28746830

8

Tripartite assembly of RND multidrug efflux pumps.

Daury L, Orange F, Taveau JC, Verchère A, Monlezun L, Gounou C, Marreddy RK, Picard M, Broutin I, Pos KM, Lambert O. Daury L, et al. Nat Commun. 2016 Feb 12;7:10731. doi: 10.1038/ncomms10731. Nat Commun. 2016. PMID: 26867482 Free PMC article.

9

The response of Lactococcus lactis to membrane protein production.

Marreddy RK, Pinto JP, Wolters JC, Geertsma ER, Fusetti F, Permentier HP, Kuipers OP, Kok J, Poolman B. Marreddy RK, et al. PLoS One. 2011;6(8):e24060. doi: 10.1371/journal.pone.0024060. Epub 2011 Aug 31. PLoS One. 2011. PMID: 21904605 Free PMC article.

10

Efficient overproduction of membrane proteins in Lactococcus lactis requires the cell envelope stress sensor/regulator couple CesSR.

Pinto JP, Kuipers OP, Marreddy RK, Poolman B, Kok J. Pinto JP, et al. PLoS One. 2011;6(7):e21873. doi: 10.1371/journal.pone.0021873. Epub 2011 Jul 19. PLoS One. 2011. PMID: 21818275 Free PMC article.

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