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Inducible and reversible inhibition of miRNA-mediated gene repression in vivo.
La Rocca G, King B, Shui B, Li X, Zhang M, Akat KM, Ogrodowski P, Mastroleo C, Chen K, Cavalieri V, Ma Y, Anelli V, Betel D, Vidigal J, Tuschl T, Meister G, Thompson CB, Lindsten T, Haigis K, Ventura A. La Rocca G, et al. Elife. 2021 Aug 31;10:e70948. doi: 10.7554/eLife.70948. Elife. 2021. PMID: 34463618 Free PMC article.
In vivo, Argonaute-bound microRNAs exist predominantly in a reservoir of low molecular weight complexes not associated with mRNA.
La Rocca G, Olejniczak SH, González AJ, Briskin D, Vidigal JA, Spraggon L, DeMatteo RG, Radler MR, Lindsten T, Ventura A, Tuschl T, Leslie CS, Thompson CB. La Rocca G, et al. Proc Natl Acad Sci U S A. 2015 Jan 20;112(3):767-72. doi: 10.1073/pnas.1424217112. Epub 2015 Jan 7. Proc Natl Acad Sci U S A. 2015. PMID: 25568082 Free PMC article.
High-Resolution In Vivo Identification of miRNA Targets by Halo-Enhanced Ago2 Pull-Down.
Li X, Pritykin Y, Concepcion CP, Lu Y, La Rocca G, Zhang M, King B, Cook PJ, Au YW, Popow O, Paulo JA, Otis HG, Mastroleo C, Ogrodowski P, Schreiner R, Haigis KM, Betel D, Leslie CS, Ventura A. Li X, et al. Among authors: la rocca g. Mol Cell. 2020 Jul 2;79(1):167-179.e11. doi: 10.1016/j.molcel.2020.05.009. Epub 2020 Jun 3. Mol Cell. 2020. PMID: 32497496 Free PMC article.
Interplay between K-RAS and miRNAs.
Shui B, La Rocca G, Ventura A, Haigis KM. Shui B, et al. Among authors: la rocca g. Trends Cancer. 2022 May;8(5):384-396. doi: 10.1016/j.trecan.2022.01.002. Epub 2022 Jan 31. Trends Cancer. 2022. PMID: 35093302 Free PMC article. Review.
The Multiplicity of Argonaute Complexes in Mammalian Cells.
Mauro M, Berretta M, Palermo G, Cavalieri V, La Rocca G. Mauro M, et al. Among authors: la rocca g. J Pharmacol Exp Ther. 2023 Jan;384(1):1-9. doi: 10.1124/jpet.122.001158. Epub 2022 Jun 6. J Pharmacol Exp Ther. 2023. PMID: 35667689 Free PMC article. Review.
Oncogenic K-Ras suppresses global miRNA function.
Shui B, Beyett TS, Chen Z, Li X, La Rocca G, Gazlay WM, Eck MJ, Lau KS, Ventura A, Haigis KM. Shui B, et al. Among authors: la rocca g. Mol Cell. 2023 Jul 20;83(14):2509-2523.e13. doi: 10.1016/j.molcel.2023.06.008. Epub 2023 Jul 3. Mol Cell. 2023. PMID: 37402366
252 results