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A humanized orthotopic tumor microenvironment alters the bone metastatic tropism of prostate cancer cells.
Commun Biol. 2021 Aug 30;4(1):1014. doi: 10.1038/s42003-021-02527-x.
Commun Biol. 2021.
PMID: 34462519
Free PMC article.
Engineering a humanized bone organ model in mice to study bone metastases.
Martine LC, Holzapfel BM, McGovern JA, Wagner F, Quent VM, Hesami P, Wunner FM, Vaquette C, De-Juan-Pardo EM, Brown TD, Nowlan B, Wu DJ, Hutmacher CO, Moi D, Oussenko T, Piccinini E, Zandstra PW, Mazzieri R, Lévesque JP, Dalton PD, Taubenberger AV, Hutmacher DW.
Martine LC, et al.
Nat Protoc. 2017 Apr;12(4):639-663. doi: 10.1038/nprot.2017.002. Epub 2017 Mar 2.
Nat Protoc. 2017.
PMID: 28253234
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Humanization of bone and bone marrow in an orthotopic site reveals new potential therapeutic targets in osteosarcoma.
Wagner F, Holzapfel BM, McGovern JA, Shafiee A, Baldwin JG, Martine LC, Lahr CA, Wunner FM, Friis T, Bas O, Boxberg M, Prodinger PM, Shokoohmand A, Moi D, Mazzieri R, Loessner D, Hutmacher DW.
Wagner F, et al. Among authors: martine lc.
Biomaterials. 2018 Jul;171:230-246. doi: 10.1016/j.biomaterials.2018.04.030. Epub 2018 Apr 16.
Biomaterials. 2018.
PMID: 29705656
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A humanized bone microenvironment uncovers HIF2 alpha as a latent marker for osteosarcoma.
Wagner F, Holzapfel BM, Martine LC, McGovern J, Lahr CA, Boxberg M, Prodinger PM, Grässel S, Loessner D, Hutmacher DW.
Wagner F, et al. Among authors: martine lc.
Acta Biomater. 2019 Apr 15;89:372-381. doi: 10.1016/j.actbio.2019.02.051. Epub 2019 Mar 2.
Acta Biomater. 2019.
PMID: 30836200
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Periosteum tissue engineering in an orthotopic in vivo platform.
Baldwin JG, Wagner F, Martine LC, Holzapfel BM, Theodoropoulos C, Bas O, Savi FM, Werner C, De-Juan-Pardo EM, Hutmacher DW.
Baldwin JG, et al. Among authors: martine lc.
Biomaterials. 2017 Mar;121:193-204. doi: 10.1016/j.biomaterials.2016.11.016. Epub 2016 Nov 20.
Biomaterials. 2017.
PMID: 28092776
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A humanised tissue-engineered bone model allows species-specific breast cancer-related bone metastasis in vivo.
Quent V, Taubenberger AV, Reichert JC, Martine LC, Clements JA, Hutmacher DW, Loessner D.
Quent V, et al. Among authors: martine lc.
J Tissue Eng Regen Med. 2018 Feb;12(2):494-504. doi: 10.1002/term.2517. Epub 2017 Nov 29.
J Tissue Eng Regen Med. 2018.
PMID: 28714574
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Tissue engineering and regenerative medicine in musculoskeletal oncology.
Holzapfel BM, Wagner F, Martine LC, Reppenhagen S, Rudert M, Schuetz M, Denham J, Schantz JT, Hutmacher DW.
Holzapfel BM, et al. Among authors: martine lc.
Cancer Metastasis Rev. 2016 Sep;35(3):475-87. doi: 10.1007/s10555-016-9635-z.
Cancer Metastasis Rev. 2016.
PMID: 27566370
Review.
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Functionalization, preparation and use of cell-laden gelatin methacryloyl-based hydrogels as modular tissue culture platforms.
Loessner D, Meinert C, Kaemmerer E, Martine LC, Yue K, Levett PA, Klein TJ, Melchels FP, Khademhosseini A, Hutmacher DW.
Loessner D, et al. Among authors: martine lc.
Nat Protoc. 2016 Apr;11(4):727-46. doi: 10.1038/nprot.2016.037. Epub 2016 Mar 17.
Nat Protoc. 2016.
PMID: 26985572
Free article.
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