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A humanized orthotopic tumor microenvironment alters the bone metastatic tropism of prostate cancer cells.
McGovern JA, Bock N, Shafiee A, Martine LC, Wagner F, Baldwin JG, Landgraf M, Lahr CA, Meinert C, Williams ED, Pollock PM, Denham J, Russell PJ, Risbridger GP, Clements JA, Loessner D, Holzapfel BM, Hutmacher DW. McGovern JA, et al. Among authors: lahr ca. Commun Biol. 2021 Aug 30;4(1):1014. doi: 10.1038/s42003-021-02527-x. Commun Biol. 2021. PMID: 34462519 Free PMC article.
Humanization of bone and bone marrow in an orthotopic site reveals new potential therapeutic targets in osteosarcoma.
Wagner F, Holzapfel BM, McGovern JA, Shafiee A, Baldwin JG, Martine LC, Lahr CA, Wunner FM, Friis T, Bas O, Boxberg M, Prodinger PM, Shokoohmand A, Moi D, Mazzieri R, Loessner D, Hutmacher DW. Wagner F, et al. Among authors: lahr ca. Biomaterials. 2018 Jul;171:230-246. doi: 10.1016/j.biomaterials.2018.04.030. Epub 2018 Apr 16. Biomaterials. 2018. PMID: 29705656
Targeted camptothecin delivery via silicon nanoparticles reduces breast cancer metastasis.
Landgraf M, Lahr CA, Kaur I, Shafiee A, Sanchez-Herrero A, Janowicz PW, Ravichandran A, Howard CB, Cifuentes-Rius A, McGovern JA, Voelcker NH, Hutmacher DW. Landgraf M, et al. Among authors: lahr ca. Biomaterials. 2020 May;240:119791. doi: 10.1016/j.biomaterials.2020.119791. Epub 2020 Jan 17. Biomaterials. 2020. PMID: 32109589
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