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Influenza virus-like particles produced by transient expression in Nicotiana benthamiana induce a protective immune response against a lethal viral challenge in mice.
D'Aoust MA, Lavoie PO, Couture MM, Trépanier S, Guay JM, Dargis M, Mongrand S, Landry N, Ward BJ, Vézina LP. D'Aoust MA, et al. Among authors: trepanier s. Plant Biotechnol J. 2008 Dec;6(9):930-40. doi: 10.1111/j.1467-7652.2008.00384.x. Plant Biotechnol J. 2008. PMID: 19076615 Free article.
Immunogenicity and safety of a quadrivalent plant-derived virus like particle influenza vaccine candidate-Two randomized Phase II clinical trials in 18 to 49 and ≥50 years old adults.
Pillet S, Couillard J, Trépanier S, Poulin JF, Yassine-Diab B, Guy B, Ward BJ, Landry N. Pillet S, et al. Among authors: trepanier s. PLoS One. 2019 Jun 5;14(6):e0216533. doi: 10.1371/journal.pone.0216533. eCollection 2019. PLoS One. 2019. PMID: 31166987 Free PMC article. Clinical Trial.
Efficacy, immunogenicity, and safety of a plant-derived, quadrivalent, virus-like particle influenza vaccine in adults (18-64 years) and older adults (≥65 years): two multicentre, randomised phase 3 trials.
Ward BJ, Makarkov A, Séguin A, Pillet S, Trépanier S, Dhaliwall J, Libman MD, Vesikari T, Landry N. Ward BJ, et al. Among authors: trepanier s. Lancet. 2020 Nov 7;396(10261):1491-1503. doi: 10.1016/S0140-6736(20)32014-6. Epub 2020 Oct 13. Lancet. 2020. PMID: 33065035 Clinical Trial.
Phase 1 randomized trial of a plant-derived virus-like particle vaccine for COVID-19.
Ward BJ, Gobeil P, Séguin A, Atkins J, Boulay I, Charbonneau PY, Couture M, D'Aoust MA, Dhaliwall J, Finkle C, Hager K, Mahmood A, Makarkov A, Cheng MP, Pillet S, Schimke P, St-Martin S, Trépanier S, Landry N. Ward BJ, et al. Among authors: trepanier s. Nat Med. 2021 Jun;27(6):1071-1078. doi: 10.1038/s41591-021-01370-1. Epub 2021 May 18. Nat Med. 2021. PMID: 34007070 Free PMC article. Clinical Trial.
75 results