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Non-canonical role of Hippo tumor suppressor serine/threonine kinase 3 STK3 in prostate cancer.
Schirmer AU, Driver LM, Zhao MT, Wells CI, Pickett JE, O'Bryne SN, Eduful BJ, Yang X, Howard L, You S, Devi GR, DiGiovanni J, Freedland SJ, Chi JT, Drewry DH, Macias E. Schirmer AU, et al. Among authors: you s. Mol Ther. 2022 Jan 5;30(1):485-500. doi: 10.1016/j.ymthe.2021.08.029. Epub 2021 Aug 25. Mol Ther. 2022. PMID: 34450249 Free PMC article.
ONECUT2 is a targetable master regulator of lethal prostate cancer that suppresses the androgen axis.
Rotinen M, You S, Yang J, Coetzee SG, Reis-Sobreiro M, Huang WC, Huang F, Pan X, Yáñez A, Hazelett DJ, Chu CY, Steadman K, Morrissey CM, Nelson PS, Corey E, Chung LWK, Freedland SJ, Di Vizio D, Garraway IP, Murali R, Knudsen BS, Freeman MR. Rotinen M, et al. Among authors: you s. Nat Med. 2018 Dec;24(12):1887-1898. doi: 10.1038/s41591-018-0241-1. Epub 2018 Nov 26. Nat Med. 2018. PMID: 30478421 Free PMC article.
Validation of a genomic classifier for prediction of metastasis and prostate cancer-specific mortality in African-American men following radical prostatectomy in an equal access healthcare setting.
Howard LE, Zhang J, Fishbane N, Hoedt AM, Klaassen Z, Spratt DE, Vidal AC, Lin D, Hitchins MP, You S, Freeman MR, Yamoah K, Davicioni E, Freedland SJ. Howard LE, et al. Among authors: you s. Prostate Cancer Prostatic Dis. 2020 Sep;23(3):419-428. doi: 10.1038/s41391-019-0197-3. Epub 2019 Dec 16. Prostate Cancer Prostatic Dis. 2020. PMID: 31844180
27-Hydroxycholesterol Impairs Plasma Membrane Lipid Raft Signaling as Evidenced by Inhibition of IL6-JAK-STAT3 Signaling in Prostate Cancer Cells.
Dambal S, Alfaqih M, Sanders S, Maravilla E, Ramirez-Torres A, Galvan GC, Reis-Sobreiro M, Rotinen M, Driver LM, Behrove MS, Talisman TJ, Yoon J, You S, Turkson J, Chi JT, Freeman MR, Macias E, Freedland SJ. Dambal S, et al. Among authors: you s. Mol Cancer Res. 2020 May;18(5):671-684. doi: 10.1158/1541-7786.MCR-19-0974. Epub 2020 Feb 4. Mol Cancer Res. 2020. PMID: 32019810 Free PMC article.
Comparative Genomics Reveals Distinct Immune-oncologic Pathways in African American Men with Prostate Cancer.
Awasthi S, Berglund A, Abraham-Miranda J, Rounbehler RJ, Kensler K, Serna A, Vidal A, You S, Freeman MR, Davicioni E, Liu Y, Karnes RJ, Klein EA, Den RB, Trock BJ, Campbell JD, Einstein DJ, Gupta R, Balk S, Lal P, Park JY, Cleveland JL, Rebbeck TR, Freedland SJ, Yamoah K. Awasthi S, et al. Among authors: you s. Clin Cancer Res. 2021 Jan 1;27(1):320-329. doi: 10.1158/1078-0432.CCR-20-2925. Epub 2020 Oct 9. Clin Cancer Res. 2021. PMID: 33037017 Free PMC article.
A comparative study of PCS and PAM50 prostate cancer classification schemes.
Yoon J, Kim M, Posadas EM, Freedland SJ, Liu Y, Davicioni E, Den RB, Trock BJ, Karnes RJ, Klein EA, Freeman MR, You S. Yoon J, et al. Among authors: you s. Prostate Cancer Prostatic Dis. 2021 Sep;24(3):733-742. doi: 10.1038/s41391-021-00325-4. Epub 2021 Feb 2. Prostate Cancer Prostatic Dis. 2021. PMID: 33531653 Free PMC article.
Loss of CDCP1 triggers FAK activation in detached prostate cancer cells.
Pollan SG, Teng PC, Jan YJ, Livingstone J, Huang C, Kim M, Mariscal J, Rodriguez M, Chen JF, You S, DiVizio D, Boutros PC, Chan KS, Rasorenova O, Cress A, Spassov D, Moasser M, Posadas EM, Freedland SJ, Freeman MR, Zheng JJ, Knudsen BS. Pollan SG, et al. Among authors: you s. Am J Clin Exp Urol. 2021 Aug 25;9(4):350-366. eCollection 2021. Am J Clin Exp Urol. 2021. PMID: 34541033 Free PMC article.
NUAK family kinase 2 is a novel therapeutic target for prostate cancer.
Fu W, Zhao MT, Driver LM, Schirmer AU, Yin Q, You S, Freedland SJ, DiGiovanni J, Drewry DH, Macias E. Fu W, et al. Among authors: you s. Mol Carcinog. 2022 Mar;61(3):334-345. doi: 10.1002/mc.23374. Epub 2021 Nov 24. Mol Carcinog. 2022. PMID: 34818445
3,528 results