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N-Terminal Liver-Expressed Antimicrobial Peptide 2 (LEAP2) Region Exhibits Inverse Agonist Activity toward the Ghrelin Receptor.
M'Kadmi C, Cabral A, Barrile F, Giribaldi J, Cantel S, Damian M, Mary S, Denoyelle S, Dutertre S, Péraldi-Roux S, Neasta J, Oiry C, Banères JL, Marie J, Perello M, Fehrentz JA. M'Kadmi C, et al. Among authors: peraldi roux s. J Med Chem. 2019 Jan 24;62(2):965-973. doi: 10.1021/acs.jmedchem.8b01644. Epub 2018 Dec 24. J Med Chem. 2019. PMID: 30543423
Design and characterization of a triazole-based growth hormone secretagogue receptor modulator inhibiting the glucoregulatory and feeding actions of ghrelin.
Péraldi-Roux S, Bayle M, M'Kadmi C, Damian M, Vaillé J, Fernandez G, Cornejo MP, Marie J, Banères JL, Ben Haj Salah K, Fehrentz JA, Cantel S, Perello M, Denoyelle S, Oiry C, Neasta J. Péraldi-Roux S, et al. Biochem Pharmacol. 2022 Aug;202:115114. doi: 10.1016/j.bcp.2022.115114. Epub 2022 May 31. Biochem Pharmacol. 2022. PMID: 35659880
Development of Nonpeptidic Inverse Agonists of the Ghrelin Receptor (GHSR) Based on the 1,2,4-Triazole Scaffold.
Haj Salah KB, Maingot M, Blayo AL, M'Kadmi C, Damian M, Mary S, Cantel S, Neasta J, Oiry C, Péraldi-Roux S, Fernandez G, Romero GG, Perello M, Marie J, Banères JL, Fehrentz JA, Denoyelle S. Haj Salah KB, et al. Among authors: peraldi roux s. J Med Chem. 2020 Oct 8;63(19):10796-10815. doi: 10.1021/acs.jmedchem.9b02122. Epub 2020 Sep 21. J Med Chem. 2020. PMID: 32882134
Reduced production of isoprostanes by peri-pancreatic adipose tissue from Zucker fa/fa rats as a new mechanism for β-cell compensation in insulin resistance and obesity.
Laget J, Vigor C, Nouvel A, Rocher A, Leroy J, Jeanson L, Reversat G, Oger C, Galano JM, Durand T, Péraldi-Roux S, Azay-Milhau J, Lajoix AD. Laget J, et al. Among authors: peraldi roux s. Free Radic Biol Med. 2022 Mar;182:160-170. doi: 10.1016/j.freeradbiomed.2022.02.013. Epub 2022 Feb 25. Free Radic Biol Med. 2022. PMID: 35227851
42 results