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Safety and tolerability of a single administration of AR-301, a human monoclonal antibody, in ICU patients with severe pneumonia caused by Staphylococcus aureus: first-in-human trial.
François B, Mercier E, Gonzalez C, Asehnoune K, Nseir S, Fiancette M, Desachy A, Plantefève G, Meziani F, de Lame PA, Laterre PF; MASTER 1 study group. François B, et al. Intensive Care Med. 2018 Nov;44(11):1787-1796. doi: 10.1007/s00134-018-5229-2. Epub 2018 Oct 21. Intensive Care Med. 2018. PMID: 30343314 Clinical Trial.
SARS-CoV-2 causes a specific dysfunction of the kidney proximal tubule.
Werion A, Belkhir L, Perrot M, Schmit G, Aydin S, Chen Z, Penaloza A, De Greef J, Yildiz H, Pothen L, Yombi JC, Dewulf J, Scohy A, Gérard L, Wittebole X, Laterre PF, Miller SE, Devuyst O, Jadoul M, Morelle J; Cliniques universitaires Saint-Luc (CUSL) COVID-19 Research Group. Werion A, et al. Kidney Int. 2020 Nov;98(5):1296-1307. doi: 10.1016/j.kint.2020.07.019. Epub 2020 Aug 10. Kidney Int. 2020. PMID: 32791255 Free PMC article.
Inhibition of aquaporin-1 prevents myocardial remodeling by blocking the transmembrane transport of hydrogen peroxide.
Montiel V, Bella R, Michel LYM, Esfahani H, De Mulder D, Robinson EL, Deglasse JP, Tiburcy M, Chow PH, Jonas JC, Gilon P, Steinhorn B, Michel T, Beauloye C, Bertrand L, Farah C, Dei Zotti F, Debaix H, Bouzin C, Brusa D, Horman S, Vanoverschelde JL, Bergmann O, Gilis D, Rooman M, Ghigo A, Geninatti-Crich S, Yool A, Zimmermann WH, Roderick HL, Devuyst O, Balligand JL. Montiel V, et al. Sci Transl Med. 2020 Oct 7;12(564):eaay2176. doi: 10.1126/scitranslmed.aay2176. Sci Transl Med. 2020. PMID: 33028705
Serum uric acid, disease severity and outcomes in COVID-19.
Dufour I, Werion A, Belkhir L, Wisniewska A, Perrot M, De Greef J, Schmit G, Yombi JC, Wittebole X, Laterre PF, Jadoul M, Gérard L, Morelle J; CUSL COVID-19 Research Group. Dufour I, et al. Crit Care. 2021 Jun 14;25(1):212. doi: 10.1186/s13054-021-03616-3. Crit Care. 2021. PMID: 34127048 Free PMC article.
Safety and tolerability of non-neutralizing adrenomedullin antibody adrecizumab (HAM8101) in septic shock patients: the AdrenOSS-2 phase 2a biomarker-guided trial.
Laterre PF, Pickkers P, Marx G, Wittebole X, Meziani F, Dugernier T, Huberlant V, Schuerholz T, François B, Lascarrou JB, Beishuizen A, Oueslati H, Contou D, Hoiting O, Lacherade JC, Chousterman B, Pottecher J, Bauer M, Godet T, Karakas M, Helms J, Bergmann A, Zimmermann J, Richter K, Hartmann O, Pars M, Mebazaa A; AdrenOSS-2 study participants. Laterre PF, et al. Intensive Care Med. 2021 Nov;47(11):1284-1294. doi: 10.1007/s00134-021-06537-5. Epub 2021 Oct 4. Intensive Care Med. 2021. PMID: 34605947 Free PMC article. Clinical Trial.
Inflammation-Induced Coagulopathy Substantially Differs Between COVID-19 and Septic Shock: A Prospective Observational Study.
Dechamps M, De Poortere J, Martin M, Gatto L, Daumerie A, Bouzin C, Octave M, Ginion A, Robaux V, Pirotton L, Bodart J, Gerard L, Montiel V, Campion A, Gruson D, Van Dievoet MA, Douxfils J, Haguet H, Morimont L, Derive M, Jolly L, Bertrand L, Dumoutier L, Castanares-Zapatero D, Laterre PF, Horman S, Beauloye C. Dechamps M, et al. Among authors: montiel v. Front Med (Lausanne). 2022 Jan 17;8:780750. doi: 10.3389/fmed.2021.780750. eCollection 2021. Front Med (Lausanne). 2022. PMID: 35111777 Free PMC article.
Oxidative stress-induced endothelial dysfunction and decreased vascular nitric oxide in COVID-19 patients.
Montiel V, Lobysheva I, Gérard L, Vermeersch M, Perez-Morga D, Castelein T, Mesland JB, Hantson P, Collienne C, Gruson D, van Dievoet MA, Persu A, Beauloye C, Dechamps M, Belkhir L, Robert A, Derive M, Laterre PF, Danser AHJ, Wittebole X, Balligand JL. Montiel V, et al. EBioMedicine. 2022 Mar;77:103893. doi: 10.1016/j.ebiom.2022.103893. Epub 2022 Feb 23. EBioMedicine. 2022. PMID: 35219085 Free PMC article.
81 results