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The Unfolded Protein Response Is a Major Driver of LCN2 Expression in BCR-ABL- and JAK2V617F-Positive MPN.
Tillmann S, Olschok K, Schröder SK, Bütow M, Baumeister J, Kalmer M, Preußger V, Weinbergerova B, Kricheldorf K, Mayer J, Kubesova B, Racil Z, Wessiepe M, Eschweiler J, Isfort S, Brümmendorf TH, Becker W, Schemionek M, Weiskirchen R, Koschmieder S, Chatain N. Tillmann S, et al. Among authors: brummendorf th. Cancers (Basel). 2021 Aug 21;13(16):4210. doi: 10.3390/cancers13164210. Cancers (Basel). 2021. PMID: 34439364 Free PMC article.
Epimutations mimic genomic mutations of DNMT3A in acute myeloid leukemia.
Jost E, Lin Q, Weidner CI, Wilop S, Hoffmann M, Walenda T, Schemionek M, Herrmann O, Zenke M, Brümmendorf TH, Koschmieder S, Wagner W. Jost E, et al. Among authors: brummendorf th. Leukemia. 2014 Jun;28(6):1227-34. doi: 10.1038/leu.2013.362. Epub 2013 Nov 27. Leukemia. 2014. PMID: 24280869 Free PMC article.
A 'telomere-associated secretory phenotype' cooperates with BCR-ABL to drive malignant proliferation of leukemic cells.
Braig M, Pällmann N, Preukschas M, Steinemann D, Hofmann W, Gompf A, Streichert T, Braunschweig T, Copland M, Rudolph KL, Bokemeyer C, Koschmieder S, Schuppert A, Balabanov S, Brümmendorf TH. Braig M, et al. Among authors: brummendorf th. Leukemia. 2014 Oct;28(10):2028-39. doi: 10.1038/leu.2014.95. Epub 2014 Mar 7. Leukemia. 2014. PMID: 24603533
Bosutinib: a novel second-generation tyrosine kinase inhibitor.
Isfort S, Keller-v Amsberg G, Schafhausen P, Koschmieder S, Brümmendorf TH. Isfort S, et al. Among authors: brummendorf th. Recent Results Cancer Res. 2014;201:81-97. doi: 10.1007/978-3-642-54490-3_4. Recent Results Cancer Res. 2014. PMID: 24756786 Review.
Activated fibronectin-secretory phenotype of mesenchymal stromal cells in pre-fibrotic myeloproliferative neoplasms.
Schneider RK, Ziegler S, Leisten I, Ferreira MS, Schumacher A, Rath B, Fahrenkamp D, Müller-Newen G, Crysandt M, Wilop S, Jost E, Koschmieder S, Knüchel R, Brümmendorf TH, Ziegler P. Schneider RK, et al. Among authors: brummendorf th. J Hematol Oncol. 2014 Dec 14;7:92. doi: 10.1186/s13045-014-0092-2. J Hematol Oncol. 2014. PMID: 25498831 Free PMC article.
JAK Inhibition Impairs NK Cell Function in Myeloproliferative Neoplasms.
Schönberg K, Rudolph J, Vonnahme M, Parampalli Yajnanarayana S, Cornez I, Hejazi M, Manser AR, Uhrberg M, Verbeek W, Koschmieder S, Brümmendorf TH, Brossart P, Heine A, Wolf D. Schönberg K, et al. Among authors: brummendorf th. Cancer Res. 2015 Jun 1;75(11):2187-99. doi: 10.1158/0008-5472.CAN-14-3198. Epub 2015 Apr 1. Cancer Res. 2015. PMID: 25832652
Dissecting Genomic Aberrations in Myeloproliferative Neoplasms by Multiplex-PCR and Next Generation Sequencing.
Kirschner MM, Schemionek M, Schubert C, Chatain N, Sontag S, Isfort S, Ortiz-Brüchle N, Schmitt K, Krüger L, Zerres K, Zenke M, Brümmendorf TH, Koschmieder S. Kirschner MM, et al. Among authors: brummendorf th. PLoS One. 2015 Apr 20;10(4):e0123476. doi: 10.1371/journal.pone.0123476. eCollection 2015. PLoS One. 2015. PMID: 25894969 Free PMC article.
Identification of the Adapter Molecule MTSS1 as a Potential Oncogene-Specific Tumor Suppressor in Acute Myeloid Leukemia.
Schemionek M, Kharabi Masouleh B, Klaile Y, Krug U, Hebestreit K, Schubert C, Dugas M, Büchner T, Wörmann B, Hiddemann W, Berdel WE, Brümmendorf TH, Müller-Tidow C, Koschmieder S. Schemionek M, et al. Among authors: brummendorf th. PLoS One. 2015 May 21;10(5):e0125783. doi: 10.1371/journal.pone.0125783. eCollection 2015. PLoS One. 2015. PMID: 25996952 Free PMC article.
Mtss1 is a critical epigenetically regulated tumor suppressor in CML.
Schemionek M, Herrmann O, Reher MM, Chatain N, Schubert C, Costa IG, Hänzelmann S, Gusmao EG, Kintsler S, Braunschweig T, Hamilton A, Helgason GV, Copland M, Schwab A, Müller-Tidow C, Li S, Holyoake TL, Brümmendorf TH, Koschmieder S. Schemionek M, et al. Among authors: brummendorf th. Leukemia. 2016 Apr;30(4):823-32. doi: 10.1038/leu.2015.329. Epub 2015 Dec 1. Leukemia. 2016. PMID: 26621336 Free article.
362 results