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Amyloid-β toxicity modulates tau phosphorylation through the PAX6 signalling pathway.
Zhang Y, Zhang Y, Aman Y, Ng CT, Chau WH, Zhang Z, Yue M, Bohm C, Jia Y, Li S, Yuan Q, Griffin J, Chiu K, Wong DSM, Wang B, Jin D, Rogaeva E, Fraser PE, Fang EF, St George-Hyslop P, Song YQ. Zhang Y, et al. Among authors: griffin j. Brain. 2021 Oct 22;144(9):2759-2770. doi: 10.1093/brain/awab134. Brain. 2021. PMID: 34428276
Wild-type sTREM2 blocks Aβ aggregation and neurotoxicity, but the Alzheimer's R47H mutant increases Aβ aggregation.
Vilalta A, Zhou Y, Sevalle J, Griffin JK, Satoh K, Allendorf DH, De S, Puigdellívol M, Bruzas A, Burguillos MA, Dodd RB, Chen F, Zhang Y, Flagmeier P, Needham LM, Enomoto M, Qamar S, Henderson J, Walter J, Fraser PE, Klenerman D, Lee SF, St George-Hyslop P, Brown GC. Vilalta A, et al. Among authors: griffin jk. J Biol Chem. 2021 Jan-Jun;296:100631. doi: 10.1016/j.jbc.2021.100631. Epub 2021 Apr 3. J Biol Chem. 2021. PMID: 33823153 Free PMC article.
4,328 results