Lees JA - Search Results

1

Acquired resistance to PRMT5 inhibition induces concomitant collateral sensitivity to paclitaxel.

Mueller HS, Fowler CE, Dalin S, Moiso E, Udomlumleart T, Garg S, Hemann MT, Lees JA. Mueller HS, et al. Among authors: lees ja. Proc Natl Acad Sci U S A. 2021 Aug 24;118(34):e2024055118. doi: 10.1073/pnas.2024055118. Proc Natl Acad Sci U S A. 2021. PMID: 34408017 Free PMC article.

2

Inhibition of cyclin-dependent kinase 2 by p21 is necessary for retinoblastoma protein-mediated G1 arrest after gamma-irradiation.

Brugarolas J, Moberg K, Boyd SD, Taya Y, Jacks T, Lees JA. Brugarolas J, et al. Among authors: lees ja. Proc Natl Acad Sci U S A. 1999 Feb 2;96(3):1002-7. doi: 10.1073/pnas.96.3.1002. Proc Natl Acad Sci U S A. 1999. PMID: 9927683 Free PMC article.

3

Regulation of the insulin-like developmental pathway of Caenorhabditis elegans by a homolog of the PTEN tumor suppressor gene.

Gil EB, Malone Link E, Liu LX, Johnson CD, Lees JA. Gil EB, et al. Among authors: lees ja. Proc Natl Acad Sci U S A. 1999 Mar 16;96(6):2925-30. doi: 10.1073/pnas.96.6.2925. Proc Natl Acad Sci U S A. 1999. PMID: 10077613 Free PMC article.

4

Tossing monkey wrenches into the clock: new ways of treating cancer.

Lees JA, Weinberg RA. Lees JA, et al. Proc Natl Acad Sci U S A. 1999 Apr 13;96(8):4221-3. doi: 10.1073/pnas.96.8.4221. Proc Natl Acad Sci U S A. 1999. PMID: 10200241 Free PMC article. Review. No abstract available.

5

Loss of p53 synthesis in zebrafish tumors with ribosomal protein gene mutations.

MacInnes AW, Amsterdam A, Whittaker CA, Hopkins N, Lees JA. MacInnes AW, et al. Among authors: lees ja. Proc Natl Acad Sci U S A. 2008 Jul 29;105(30):10408-13. doi: 10.1073/pnas.0805036105. Epub 2008 Jul 18. Proc Natl Acad Sci U S A. 2008. PMID: 18641120 Free PMC article.

6

Bmi1 is critical for lung tumorigenesis and bronchioalveolar stem cell expansion.

Dovey JS, Zacharek SJ, Kim CF, Lees JA. Dovey JS, et al. Among authors: lees ja. Proc Natl Acad Sci U S A. 2008 Aug 19;105(33):11857-62. doi: 10.1073/pnas.0803574105. Epub 2008 Aug 12. Proc Natl Acad Sci U S A. 2008. PMID: 18697930 Free PMC article.

7

Metastatic osteosarcoma induced by inactivation of Rb and p53 in the osteoblast lineage.

Berman SD, Calo E, Landman AS, Danielian PS, Miller ES, West JC, Fonhoue BD, Caron A, Bronson R, Bouxsein ML, Mukherjee S, Lees JA. Berman SD, et al. Among authors: lees ja. Proc Natl Acad Sci U S A. 2008 Aug 19;105(33):11851-6. doi: 10.1073/pnas.0805462105. Epub 2008 Aug 12. Proc Natl Acad Sci U S A. 2008. PMID: 18697945 Free PMC article.

8

Mutation of p107 exacerbates the consequences of Rb loss in embryonic tissues and causes cardiac and blood vessel defects.

Berman SD, West JC, Danielian PS, Caron AM, Stone JR, Lees JA. Berman SD, et al. Among authors: lees ja. Proc Natl Acad Sci U S A. 2009 Sep 1;106(35):14932-6. doi: 10.1073/pnas.0902408106. Epub 2009 Aug 19. Proc Natl Acad Sci U S A. 2009. PMID: 19706423 Free PMC article.

9

Highly aneuploid zebrafish malignant peripheral nerve sheath tumors have genetic alterations similar to human cancers.

Zhang G, Hoersch S, Amsterdam A, Whittaker CA, Lees JA, Hopkins N. Zhang G, et al. Among authors: lees ja. Proc Natl Acad Sci U S A. 2010 Sep 28;107(39):16940-5. doi: 10.1073/pnas.1011548107. Epub 2010 Sep 13. Proc Natl Acad Sci U S A. 2010. PMID: 20837522 Free PMC article.

10

Minor Changes in Expression of the Mismatch Repair Protein MSH2 Exert a Major Impact on Glioblastoma Response to Temozolomide.

McFaline-Figueroa JL, Braun CJ, Stanciu M, Nagel ZD, Mazzucato P, Sangaraju D, Cerniauskas E, Barford K, Vargas A, Chen Y, Tretyakova N, Lees JA, Hemann MT, White FM, Samson LD. McFaline-Figueroa JL, et al. Among authors: lees ja. Cancer Res. 2015 Aug 1;75(15):3127-38. doi: 10.1158/0008-5472.CAN-14-3616. Epub 2015 May 29. Cancer Res. 2015. PMID: 26025730 Free PMC article.

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