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Cyclin D2 overexpression drives B1a-derived MCL-like lymphoma in mice.
Pieters T, T'Sas S, Vanhee S, Almeida A, Driege Y, Roels J, Van Loocke W, Daneels W, Baens M, Marchand A, Van Trimpont M, Matthijssens F, Morscio J, Lemeire K, Lintermans B, Reunes L, Chaltin P, Offner F, Van Dorpe J, Hochepied T, Berx G, Beyaert R, Staal J, Van Vlierberghe P, Goossens S. Pieters T, et al. Among authors: van trimpont m. J Exp Med. 2021 Oct 4;218(10):e20202280. doi: 10.1084/jem.20202280. Epub 2021 Aug 18. J Exp Med. 2021. PMID: 34406363 Free PMC article.
The spleen as a sanctuary site for residual leukemic cells following ABT-199 monotherapy in ETP-ALL.
Di Grande A, Peirs S, Donovan PD, Van Trimpont M, Morscio J, Lintermans B, Reunes L, Vandamme N, Goossens S, Nguyen HA, Lavie A, Lock RB, Prehn JHM, Van Vlierberghe P, Ní Chonghaile T. Di Grande A, et al. Among authors: van trimpont m. Blood Adv. 2021 Apr 13;5(7):1963-1976. doi: 10.1182/bloodadvances.2021004177. Blood Adv. 2021. PMID: 33830207 Free PMC article.
Cell-penetrating Alphabody protein scaffolds for intracellular drug targeting.
Pannecoucke E, Van Trimpont M, Desmet J, Pieters T, Reunes L, Demoen L, Vuylsteke M, Loverix S, Vandenbroucke K, Alard P, Henderikx P, Deroo S, Baatz F, Lorent E, Thiolloy S, Somers K, McGrath Y, Van Vlierberghe P, Lasters I, Savvides SN. Pannecoucke E, et al. Among authors: van trimpont m. Sci Adv. 2021 Mar 26;7(13):eabe1682. doi: 10.1126/sciadv.abe1682. Print 2021 Mar. Sci Adv. 2021. PMID: 33771865 Free PMC article.
In vivo stabilization of a less toxic asparaginase variant leads to a durable antitumor response in acute leukemia.
Van Trimpont M, Schalk AM, De Visser Y, Nguyen HA, Reunes L, Vandemeulebroecke K, Peeters E, Su Y, Lee H, Lorenzi PL, Chan WK, Mondelaers V, De Moerloose B, Lammens T, Goossens S, Van Vlierberghe P, Lavie A. Van Trimpont M, et al. Haematologica. 2023 Feb 1;108(2):409-419. doi: 10.3324/haematol.2022.281390. Haematologica. 2023. PMID: 35979719 Free PMC article.